Das Marco, Mühlenbruch Georg, Katoh Markus, Bakai Annemarie, Salganicoff Marcos, Stanzel Sven, Mahnken Andreas H, Günther Rolf W, Wildberger Joachim E
Department of Diagnostic Radiology, RWTH Aachen University, Aachen, Germany.
Invest Radiol. 2007 May;42(5):297-302. doi: 10.1097/01.rli.0000258683.20123.c4.
The accuracy of automated volumetry for pulmonary nodules in a phantom using different CT scanner technologies from single-slice spiral CT (SSCT) to 64-slice multidetector-row CT (MDCT) was compared.
A lung phantom with 5 different categories of pulmonary nodules was scanned using a single-slice spiral CT, a 4-slice MDCT, a 16-slice MDCT and a 64-slice MDCT. Each category comprised of 7-9 nodules each (total n = 40) with different known volumes. Standard dose and low dose protocols were performed using thin and thick collimation. Image data were reconstructed at the thinnest slice thickness. Data sets were analyzed with a dedicated volumetry software. Volumes of all nodules were calculated and compared.
Mean absolute percentage error (APE) for all nodules was 8.65% (+/-7.29%) for the SSCT, 10.26% (+/-8.25%) for the 4-slice MDCT, 8.19% (+/-7.57%) for the 16-slice MDCT and 7.89% (+/-7.39%) for the 64-slice MDCT. There was statistically significant influence of the scanner type, protocol, anatomic location, and nodule volume on APE, but overall, APEs were comparable.
Computer-aided volumetry showed accurate measurements in all tested scanner types. This finding has important implications for nodule assessment and follow-up.
比较使用从单层螺旋CT（SSCT）到64层多排螺旋CT（MDCT）等不同CT扫描技术对体模中肺结节进行自动容积测量的准确性。
使用单层螺旋CT、4层MDCT、16层MDCT和64层MDCT对含有5种不同类型肺结节的肺部体模进行扫描。每个类型包含7 - 9个结节（共n = 40个），其体积各不相同。使用薄准直和厚准直进行标准剂量和低剂量扫描方案。以最薄的层厚重建图像数据。使用专用的容积测量软件分析数据集。计算并比较所有结节的体积。
SSCT对所有结节的平均绝对百分比误差（APE）为8.65%（±7.29%），4层MDCT为10.26%（±8.25%），16层MDCT为8.19%（±7.57%），64层MDCT为7.89%（±7.39%）。扫描仪类型、扫描方案、解剖位置和结节体积对APE有统计学上的显著影响，但总体而言，APE具有可比性。
计算机辅助容积测量在所有测试的扫描仪类型中均显示出准确的测量结果。这一发现对结节评估和随访具有重要意义。
