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全球范围内可用的 SARS-CoV-2 基因组数量与各国人类发展指数之间的差异。

Global Discrepancies between Numbers of Available SARS-CoV-2 Genomes and Human Development Indexes at Country Scales.

机构信息

IHU Méditerranée Infection, 19-21 Boulevard Jean Moulin, 13005 Marseille, France.

Aix-Marseille University, Institut de Recherche pour le Développement (IRD), Assistance Publique-Hôpitaux de Marseille (AP-HM), MEPHI, 27 Boulevard Jean Moulin, 13005 Marseille, France.

出版信息

Viruses. 2021 Apr 28;13(5):775. doi: 10.3390/v13050775.

DOI:10.3390/v13050775
PMID:33924778
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8145975/
Abstract

It has now been over a year since SARS-CoV-2 first emerged in China, in December 2019, and it has spread rapidly around the world. Some variants are currently considered of great concern. We aimed to analyze the numbers of SARS-CoV-2 genome sequences obtained in different countries worldwide until January 2021. On 28 January 2021, we downloaded the deposited genome sequence origin from the GISAID database, and from the "Our world in data" website we downloaded numbers of SARS-CoV-2-diagnosed cases, numbers of SARS-CoV-2-associated deaths, population size, life expectancy, gross domestic product (GDP) per capita, and human development index per country. Files were merged and data were analyzed using Microsoft Excel software. A total of 450,968 SARS-CoV-2 genomes originating from 135 countries on the 5 continents were available. When considering the 19 countries for which the number of genomes per 100 deaths was >100, six were in Europe, while eight were in Asia, three were in Oceania and two were in Africa. Six (30%) of these countries are beyond rank 75, regarding the human development index and four (20%) are beyond rank 80 regarding GDP per capita. Moreover, the comparisons of the number of genomes sequenced per 100 deaths to the human development index by country show that some Western European countries have released similar or lower numbers of genomes than many African or Asian countries with a lower human development index. Previous data highlight great discrepancies between the numbers of available SARS-CoV-2 genomes per 100 cases and deaths and the ranking of countries regarding wealth and development.

摘要

自 2019 年 12 月在中国首次出现 SARS-CoV-2 以来,已经过去了一年多,它已迅速在全球传播。目前一些变体被认为非常令人担忧。我们旨在分析截至 2021 年 1 月在全球不同国家获得的 SARS-CoV-2 基因组序列数量。2021 年 1 月 28 日,我们从 GISAID 数据库下载了已保存的基因组序列来源,从“我们的世界数据”网站下载了 SARS-CoV-2 确诊病例数、SARS-CoV-2 相关死亡人数、人口规模、预期寿命、人均国内生产总值(GDP)和每个国家的人类发展指数。合并文件并使用 Microsoft Excel 软件分析数据。共有来自 5 大洲 135 个国家的 450,968 个 SARS-CoV-2 基因组。在考虑 19 个基因组数量与每 100 例死亡人数之比超过 100 的国家时,其中 6 个位于欧洲,8 个位于亚洲,3 个位于大洋洲,2 个位于非洲。这 6 个国家(30%)在人类发展指数方面排名低于 75 位,4 个国家(20%)在人均 GDP 方面排名低于 80 位。此外,对各国每 100 例死亡测序的基因组数量与人类发展指数进行比较表明,一些西欧国家发布的基因组数量与人类发展指数较低的许多非洲或亚洲国家相似或更低。以前的数据突出了可用的 SARS-CoV-2 基因组数量与每 100 例病例和死亡人数以及国家财富和发展排名之间存在巨大差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/54db/8145975/56af51c156d8/viruses-13-00775-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/54db/8145975/56af51c156d8/viruses-13-00775-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/54db/8145975/56af51c156d8/viruses-13-00775-g002.jpg

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1
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Cell Host Microbe. 2021 May 12;29(5):747-751.e4. doi: 10.1016/j.chom.2021.04.007. Epub 2021 Apr 18.
2
Emergence and outcomes of the SARS-CoV-2 'Marseille-4' variant.SARS-CoV-2“马赛 4 号”变体的出现和结果。
Int J Infect Dis. 2021 May;106:228-236. doi: 10.1016/j.ijid.2021.03.068. Epub 2021 Mar 27.
3
Sensitivity of infectious SARS-CoV-2 B.1.1.7 and B.1.351 variants to neutralizing antibodies.
特刊征稿:2021 年新兴病毒:监测、预防、演变与控制
Viruses. 2022 Apr 15;14(4):815. doi: 10.3390/v14040815.
4
Low Represented Mutation Clustering in SARS-CoV-2 B.1.1.7 Sublineage Group with Synonymous Mutations in the E Gene.严重急性呼吸综合征冠状病毒2(SARS-CoV-2)B.1.1.7亚谱系组中低频率突变聚类及E基因中的同义突变
Diagnostics (Basel). 2021 Dec 7;11(12):2286. doi: 10.3390/diagnostics11122286.
5
Evolutionary Dynamics of Indels in SARS-CoV-2 Spike Glycoprotein.严重急性呼吸综合征冠状病毒2刺突糖蛋白中插入缺失的进化动力学
Evol Bioinform Online. 2021 Dec 6;17:11769343211064616. doi: 10.1177/11769343211064616. eCollection 2021.
6
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Front Med (Lausanne). 2021 Sep 1;8:737602. doi: 10.3389/fmed.2021.737602. eCollection 2021.
7
A Possible Role of Remdesivir and Plasma Therapy in the Selective Sweep and Emergence of New SARS-CoV-2 Variants.瑞德西韦和血浆疗法在新型严重急性呼吸综合征冠状病毒2(SARS-CoV-2)变体的选择性清除和出现中的可能作用
J Clin Med. 2021 Jul 24;10(15):3276. doi: 10.3390/jcm10153276.
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4
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Nature. 2021 May;593(7857):130-135. doi: 10.1038/s41586-021-03398-2. Epub 2021 Mar 8.
6
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Cell Host Microbe. 2021 Mar 10;29(3):463-476.e6. doi: 10.1016/j.chom.2021.02.003. Epub 2021 Feb 8.
8
Introduction into the Marseille geographical area of a mild SARS-CoV-2 variant originating from sub-Saharan Africa: An investigational study.马赛地理区域引入源自撒哈拉以南非洲地区的温和 SARS-CoV-2 变异株:一项调查研究。
Travel Med Infect Dis. 2021 Mar-Apr;40:101980. doi: 10.1016/j.tmaid.2021.101980. Epub 2021 Jan 31.
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Cell Host Microbe. 2021 Mar 10;29(3):477-488.e4. doi: 10.1016/j.chom.2021.01.014. Epub 2021 Jan 27.
10
Intractable Coronavirus Disease 2019 (COVID-19) and Prolonged Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Replication in a Chimeric Antigen Receptor-Modified T-Cell Therapy Recipient: A Case Study.嵌合抗原受体修饰 T 细胞治疗受体中难治性 2019 年冠状病毒病(COVID-19)和持续严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)复制:病例研究。
Clin Infect Dis. 2021 Aug 2;73(3):e815-e821. doi: 10.1093/cid/ciab072.