Yamamoto Y, Muramatsu K
Department of Food and Nutrition, Faculty of Science of Living, Osaka City University, Japan.
J Nutr Sci Vitaminol (Tokyo). 1988 Feb;34(1):107-16. doi: 10.3177/jnsv.34.107.
The present investigation was conducted to determine if rats can recognize the essential fatty acid (EFA) in the diet. Weanling rats were pre-fed a 30% hydrogenated coconut oil (30HCO) diet containing 1% cholesterol for 2 or 4 weeks to produce EFA deficiency, then allowed to choose between the fat-free (FF) diet and the 0.5, 1.0, or 2.0% corn oil diet, and between the 0.5% HCO diet and 0.5% corn oil diet. Rats pre-fed the 30HCO diet for 2 weeks selected the corn oil-containing diets for a few days at the beginning of the experiment, but the rats pre-fed for 4 weeks could not recognize the EFA-containing diet. The non pre-fed animals continued to prefer the EFA-containing diet for about 2 weeks. From these results we could demonstrate that rats have a mechanism to distinguish the EFA in their diet, but this EFA selection ability was only in the early period of the experiment, and diminished soon after.
本研究旨在确定大鼠是否能够识别饮食中的必需脂肪酸（EFA）。将断乳大鼠预先饲喂含1%胆固醇的30%氢化椰子油（30HCO）饮食2周或4周以产生必需脂肪酸缺乏，然后让它们在无脂（FF）饮食与0.5%、1.0%或2.0%玉米油饮食之间进行选择，以及在0.5% HCO饮食和0.5%玉米油饮食之间进行选择。预先饲喂30HCO饮食2周的大鼠在实验开始时的几天内选择了含玉米油的饮食，但预先饲喂4周的大鼠无法识别含必需脂肪酸的饮食。未预先饲喂的动物在大约2周内持续偏好含必需脂肪酸的饮食。从这些结果我们可以证明，大鼠具有区分饮食中必需脂肪酸的机制，但这种必需脂肪酸选择能力仅在实验早期存在，并且很快就会减弱。
