肺减容术后的预期寿命和下降率。

Life Expectancy and Rate of Decline After Lung Volume Reduction Surgery.

机构信息

Division of Cardiothoracic Surgery, Department of Surgery, SIU School of Medicine, 701 North 1st Street, Springfield, IL 62794-9679, USA; Center for Clinical Research, SIU School of Medicine, 701 North 1st Street, Springfield, IL 62794-9679, USA.

Division of Cardiothoracic Surgery, Department of Surgery, SIU School of Medicine, 701 North 1st Street, Springfield, IL 62794-9679, USA.

出版信息

Thorac Surg Clin. 2021 May;31(2):177-188. doi: 10.1016/j.thorsurg.2021.01.001.

DOI:10.1016/j.thorsurg.2021.01.001

PMID:33926671

Abstract

Lung volume reduction surgery (LVRS) patient selection guidelines are based on the National Emphysema Treatment Trial. Because of increased mortality and poor improvement in functional outcomes, patients with non-upper lobe emphysema and low baseline exercise capacity are determined as poor candidates for LVRS. In well-selected patients with heterogeneous emphysema, LVRS has a durable long-term outcome at up to 5-years of follow-up. Five-year survival rates in patients range between 63% and 78%. LVRS seems a durable alternative for end-stage heterogeneous emphysema in patients not eligible for lung transplantation. Future studies will help identify eligible patients with homogeneous emphysema for LVRS.

摘要

肺减容手术 (LVRS) 患者选择指南基于国家肺气肿治疗试验。由于死亡率增加和功能结果改善不佳，非上叶肺气肿和低基线运动能力的患者被认为是 LVRS 的不良候选者。在选择良好的异质性肺气肿患者中，LVRS 在长达 5 年的随访中具有持久的长期结果。患者的 5 年生存率在 63%至 78%之间。对于不符合肺移植条件的终末期异质性肺气肿患者，LVRS 似乎是一种持久的替代方法。未来的研究将有助于确定适合 LVRS 的同质肺气肿患者。