Division of Neuroimaging and Neurointervention, Department of Radiology, Stanford University, 300 Pasteur Drive, Grant Building, Room S031, Stanford, CA 94305-5105, USA.
Division of Neuroimaging and Neurointervention, Department of Radiology, Stanford University, 300 Pasteur Drive, Grant Building, Room S047, Stanford, CA 94305-5105, USA. Electronic address: https://twitter.com/mwNRAD.
Radiol Clin North Am. 2021 May;59(3):323-334. doi: 10.1016/j.rcl.2021.01.002. Epub 2021 Mar 23.
Neuroimaging plays an essential role in the initial diagnosis and continued surveillance of intracranial neoplasms. The advent of perfusion techniques with computed tomography and MR imaging have proven useful in neuro-oncology, offering enhanced approaches for tumor grading, guiding stereotactic biopsies, and monitoring treatment efficacy. Perfusion imaging can help to identify treatment-related processes, such as radiation necrosis, pseudoprogression, and pseudoregression, and can help to inform treatment-related decision making. Perfusion imaging is useful to differentiate between tumor types and between tumor and nonneoplastic conditions. This article reviews the clinical relevance and implications of perfusion imaging in neuro-oncology and highlights promising perfusion biomarkers.
神经影像学在颅内肿瘤的初步诊断和持续监测中起着至关重要的作用。CT 和 MR 成像灌注技术的出现已被证明在神经肿瘤学中非常有用，为肿瘤分级、引导立体定向活检和监测治疗效果提供了增强的方法。灌注成像可以帮助识别与治疗相关的过程，如放射性坏死、假性进展和假性缓解，并有助于为治疗相关的决策提供信息。灌注成像有助于区分肿瘤类型、肿瘤和非肿瘤性病变。本文综述了灌注成像在神经肿瘤学中的临床意义和影响，并强调了有前途的灌注生物标志物。
