Division of Cardiology, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.
Curr Opin Cardiol. 2021 Sep 1;36(5):630-636. doi: 10.1097/HCO.0000000000000871.
Coronary artery calcification (CAC) predisposes to suboptimal revascularization outcomes after percutaneous coronary intervention (PCI). Despite the availability of several plaque modification devices, their rates of use remain low despite the prevalence of CAC encountered in clinical practice. It is important to understand how each device can be utilized in clinical practice in order to improve outcomes after PCI.
This article summarizes the most recent clinical evidence for each plaque modification device. Although rotational atherectomy is the most frequently used device for plaque modification, the use of orbital atherectomy (OA) has been increasing. Balloon-based strategies including recent studies evaluating a novel intravascular lithotripsy balloon have shed light on the benefits of nonablative devices in modifying CAC during PCI.
CAC poses significant technical challenges in achieving optimal stent results. Several intracoronary plaque modification devices are currently available and understanding the technical aspects, indications and contraindications to the use of each device is essential. Although rotational and OA are most commonly used, laser atherectomy and balloon-based devices may offer an advantage in certain lesion subsets.
经皮冠状动脉介入治疗(PCI)后,冠状动脉钙化(CAC)可导致血运重建效果不理想。尽管有多种斑块修饰装置,但尽管在临床实践中遇到 CAC 的普遍性,其使用率仍然较低。了解每种设备如何在临床实践中使用对于改善 PCI 后的结果很重要。
本文总结了每种斑块修饰装置的最新临床证据。尽管旋磨术是最常使用的斑块修饰装置,但轨道旋磨术(OA)的使用正在增加。基于球囊的策略,包括最近评估新型血管内碎石球囊的研究,揭示了非消融装置在 PCI 期间修饰 CAC 的益处。
CAC 对实现最佳支架效果构成重大技术挑战。目前有几种冠状动脉内斑块修饰装置,了解每种装置的技术方面、适应证和禁忌证至关重要。虽然旋转和 OA 最常使用,但激光旋磨术和基于球囊的装置在某些病变亚组中可能具有优势。