Inzunza-Cervantes Gustavo, García-Fajardo Erick Alfonso, Martínez-Hernández Francisco Antonio, Zazueta-Armenta Verónica, Hernandez-Marquez Jesús Omar, Herrera-Gavilanes Juan Ramón
Instituto Mexicano del Seguro Social, Centro Médico Nacional del Noroeste, Hospital de Especialidades No. 2 "Luis Donaldo Colosio Murrieta", Servicio de Cardiología, Grupo de Investigación Cardiovascular. Ciudad Obregón, Sonora, México.
Rev Med Inst Mex Seguro Soc. 2023 Nov 6;61(6):888-894. doi: 10.5281/zenodo.10064745.
Complex calcified coronary lesions are a frequent finding during percutaneous coronary intervention, representing for decades a challenge and limitation in patients with indication of revascularization, due to suboptimal angiographic results, high incidence of perioperative complications and long-term adverse events despite the multiple strategies employed, such as the use of cutting balloon, high-pressure balloons or rotational or orbital atherectomy, interventions with limitations that have hindered its routine use, recently a new plaque modification technique known as coronary intravascular lithotripsy has burst into the treatment of this complex entity, which consists in the use of a specially modified balloon for the emission of pulsatile mechanical energy (sonic pressure waves) that allows modifying the calcified plate.
By presenting a series of clinical cases and reviewing the literature, our initial experience is presented, key elements are summarized and discussed in the understanding of this new intervention technique necessary for decision making.
Coronary intravascular lithotripsy is projected as a promising technique for the modification and preparation of superficial and deep calcified coronary lesions, through microfractures that allow the apposition and effective expansion of the stent, strategy that according to different trials (Disrupt CAD series, SOLSTICE assay) and records presents a high efficiency and good safety profile, data consistent with our initial experience.
复杂钙化冠状动脉病变在经皮冠状动脉介入治疗中很常见,几十年来一直是有血运重建指征患者面临的挑战和限制因素,原因在于尽管采用了多种策略,如使用切割球囊、高压球囊或旋磨术或轨道旋切术,但血管造影结果仍不理想,围手术期并发症和长期不良事件发生率较高,这些干预措施存在局限性,阻碍了其常规应用。最近,一种名为冠状动脉血管内碎石术的新型斑块修饰技术已开始用于治疗这种复杂病变,该技术使用经过特殊改良的球囊发射脉动机械能(声压波)来改变钙化斑块。
通过展示一系列临床病例并回顾文献,介绍了我们的初步经验,总结并讨论了理解这一用于决策的新干预技术所需的关键要素。
冠状动脉血管内碎石术有望成为一种用于修饰和预处理浅表及深部钙化冠状动脉病变的技术,通过微骨折实现支架贴壁和有效扩张,根据不同试验(Disrupt CAD系列、SOLSTICE试验)及记录,该策略具有高效性和良好的安全性,数据与我们的初步经验一致。