McGovern Medical School, University of Texas Health Science Center at Houston (UTHealth).
Houston Veterans Affairs Health Services Research and Development Service Center for Innovations in Quality, Effectiveness and Safety, Michael E. DeBakey Veterans Affairs Medical Center.
Alzheimer Dis Assoc Disord. 2021;35(4):366-373. doi: 10.1097/WAD.0000000000000454.
Cognitive behavioral therapy (CBT) is a goal-oriented intervention that aims to improve detrimental emotional or behavioral distress by modifying individuals' thought processes. This review evaluates the efficacy and specific adaptations of CBT in persons with mild cognitive impairment and dementia.
A literature search of PubMed, Embase, and PsycINFO was conducted up to March 2020. Study quality was assessed using the Cochrane risk of bias criteria.
Twelve publications were identified. Seven of the studies demonstrated CBT efficacy to improve depression, anxiety, and/or quality of life. One study's positive postintervention outcome became insignificant with longer term follow up. Two of the studies improved sleep outcomes. Four studies integrated caregivers into intervention delivery. Three studies utilized content, memory, and adherence adaptations aimed to improve intervention efficacy. Two studies included adaptations to address caregiver burden and depression.
There is strong evidence to suggest that CBT is associated with improvements in anxiety, depression, and quality of life in persons with mild cognitive impairment and dementia. CBT showed a reduction in insomnia and improvements in sleep quality. However, there is insufficient evidence to draw conclusions on the effects of CBT on insomnia. These results suggest that further investigation into insomnia outcomes is needed.
认知行为疗法(CBT)是一种以目标为导向的干预措施,旨在通过改变个体的思维过程来改善有害的情绪或行为困扰。本综述评估了 CBT 在轻度认知障碍和痴呆患者中的疗效和特定适应性。
对 PubMed、Embase 和 PsycINFO 进行了文献检索,检索时间截至 2020 年 3 月。使用 Cochrane 偏倚风险标准评估研究质量。
确定了 12 篇出版物。其中 7 项研究表明 CBT 能够改善抑郁、焦虑和/或生活质量。一项研究的积极干预后结果在长期随访中变得不显著。两项研究改善了睡眠结果。四项研究将照顾者纳入干预提供中。三项研究采用了旨在提高干预效果的内容、记忆和依从性适应性。两项研究包括针对照顾者负担和抑郁的适应性调整。
有强有力的证据表明,CBT 与轻度认知障碍和痴呆患者的焦虑、抑郁和生活质量的改善有关。CBT 显示出对失眠的减少和对睡眠质量的改善。然而,尚无足够的证据得出 CBT 对失眠影响的结论。这些结果表明,需要进一步研究失眠的结果。