Thamby Abel, Seshachala Karthik, Sharma Lavanya, Thimmashetty Vani Holebasavanahalli, Balachander Srinivas, Shivakumar Venkataram, Hazari Nandita, Chhabra Harleen, Arumugham Shyam Sundar, Ts Jaisoorya, K Mohanavelu, Venkatasubramanian Ganesan, Reddy Y C Janardhan, Narayanaswamy Janardhanan C
Department of Psychiatry, OCD Clinic, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, Karnataka, India.
Department of Psychiatry, WISER Neuromodulation Program, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, Karnataka, India.
Asian J Psychiatr. 2021 Jun;60:102625. doi: 10.1016/j.ajp.2021.102625. Epub 2021 Apr 5.
The present study is a large case series evaluating the benefits of transcranial direct current stimulation (tDCS) in treatment-resistant obsessive compulsive disorder (OCD).
We reviewed the charts of 32 patients with treatment-resistant OCD who received 10-20 sessions of anodal pre-SMA tDCS.
Overall, 9 (28 %) showed at least partial response to tDCS at the end of 10-20 sessions [responders = 8 (25 %), partial responders = 1 (3%)]. Two out of three partial responders at the end of 10 sessions had response at the end of 20 sessions.
tDCS may benefit a proportion of patients with treatment-resistant OCD.
本研究是一项大型病例系列研究，旨在评估经颅直流电刺激（tDCS）在难治性强迫症（OCD）治疗中的益处。
我们回顾了32例难治性OCD患者的病历，这些患者接受了10 - 20次阳极前辅助运动区tDCS治疗。
总体而言，9例（28%）患者在10 - 20次治疗结束时至少对tDCS有部分反应[有反应者 = 8例（25%），部分有反应者 = 1例（3%）]。在10次治疗结束时的3例部分有反应者中，有2例在20次治疗结束时有反应。
tDCS可能使一部分难治性OCD患者受益。
