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磨菇云和耻骨软骨测量在髋关节发育不良的通用超声筛查中的应用:1896 例婴儿髋关节的数据。

Pulvinar and pubic cartilage measurements to refine universal ultrasound screening for developmental dysplasia of the hip: Data from 1896 infant hips.

机构信息

Department of Pediatric Surgery, University Hospital Centre, Brest, France.

Department of Pediatric Surgery, University Hospital Centre, Brest, France.

出版信息

Eur J Radiol. 2021 Jun;139:109727. doi: 10.1016/j.ejrad.2021.109727. Epub 2021 Apr 22.

Abstract

PURPOSE

Screening modalities for Developmental Dysplasia of the Hip (DDH) and indications for treatment of mild forms remain controversial. Ultrasound (US) measurement of the pubofemoral distance (PFD > 6 mm, composed of the pubic cartilage and the pulvinar) can avoid late diagnoses of DDH. A thick pubic cartilage may nevertheless lead to false positives. The purpose of this study was to establish standard measurements of pubic cartilage and pulvinar, through universal US screening, to lower false positive results and thus any overtreatment.

METHODS

This is a single-center observational prospective study conducted from December 2016 to January 2018, on infants who underwent universal US screening for DDH. The only inclusion criterion was an adjusted age between 4 and 12 weeks when US was realized. PFD measurement was made using the Couture and Tréguier method. In addition, thicknesses of pubic cartilage and pulvinar were measured on the same US section, in millimeters.

RESULTS

Nine hundred and forty-eight patients, representing 1896 hips, were included. The average value of pubic cartilage thickness was 1.25 mm ± 0.58 mm, with an upper threshold of 2.39 mm (+1.96σ). The average value of pulvinar thickness was 2.67 mm ± 0.78 mm, with an upper threshold of 4.20 mm (+1.96σ). We found high inter-observer reproducibility in pubic cartilage measurements.

CONCLUSION

Systematic measurements of pubic cartilage and pulvinar may refine therapeutic decision by identifying false positives. Patients with increased PFD due to a thick pubic cartilage >2,39 mm, without an associated pulvinar enlargement (<4,20 mm), could be therefore only monitored and not overtreated.

摘要

目的

发育性髋关节发育不良(DDH)的筛查方式和轻度病例的治疗指征仍存在争议。超声(US)测量耻骨股距(PFD>6mm,由耻骨软骨和髋臼上突组成)可避免 DDH 的迟发性诊断。然而,较厚的耻骨软骨可能导致假阳性。本研究旨在通过普遍的 US 筛查,确定耻骨软骨和髋臼上突的标准测量值,以降低假阳性结果,从而避免过度治疗。

方法

这是一项于 2016 年 12 月至 2018 年 1 月进行的单中心观察性前瞻性研究,研究对象为接受 DDH 普遍 US 筛查的婴儿。唯一的纳入标准是在进行 US 时调整的年龄在 4 至 12 周之间。PFD 测量采用 Couture 和 Tréguier 方法。此外,在同一 US 切片上测量耻骨软骨和髋臼上突的厚度,单位为毫米。

结果

共纳入 948 例患者,代表 1896 髋。耻骨软骨厚度的平均值为 1.25mm±0.58mm,上限为 2.39mm(+1.96σ)。髋臼上突厚度的平均值为 2.67mm±0.78mm,上限为 4.20mm(+1.96σ)。我们发现耻骨软骨测量的观察者间重现性较高。

结论

系统测量耻骨软骨和髋臼上突的厚度可以通过识别假阳性来优化治疗决策。由于耻骨软骨较厚(>2.39mm)导致 PFD 增加,但髋臼上突无增大(<4.20mm)的患者,仅需进行监测,而无需过度治疗。

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