Manchanda Raj Kumar, Miglani Anjali, Gupta Meeta, Meena Baljeet Singh, Chadha Vishal, Joseph Franco, Kalsi Amrit, Konthembath Pramod, Sharma Kavita, Rama Kamsali Nadigadda, Kaur Prabhjeet, Thavarayil Kannoth Jithesh, Nagrath Cheshta, Jethani Anju, Nellikka Aniyeri Shajimol, Chawla Anu, Ray Malaya Kumar, Ghuliani Manjula, Kudiyarasu Ram Kumar, Naskar Shruti, Bala Sudha, Sharma Brender
Health and Family Welfare Department, Directorate of AYUSH, Government of National Capital Territory of Delhi, New Delhi, India.
Homeopathy. 2021 Aug;110(3):160-167. doi: 10.1055/s-0041-1725989. Epub 2021 Apr 30.
BACKGROUND/OBJECTIVE: Coronavirus disease 2019 (COVID-19) is a new disease; its clinical profile and natural history are evolving. Each well-recorded case in homeopathic practice is important for deciding the future course of action. This study aims at identifying clinically useful homeopathic remedies and their prescribing symptoms using the prognostic factor research model.
This was an open-label, multi-centric, observational study performed from April 2020 to July 2020 at various public health care clinics. The data were collected prospectively from clinical practice at integrated COVID-19 care facilities in India. Good-quality cases were selected using a specific set of criteria. These cases were analyzed for elucidating prognostic factors by calculating the likelihood ratio (LR) of each frequently occurring symptom. The symptoms with high LR values (>1) were considered as prescribing indications of the specific remedy.
Out of 327 COVID-19 cases reported, 211 met the selection criteria for analysis. The most common complaints were fatigue, sore throat, dry cough, myalgia, fever, dry mouth and throat, increased thirst, headache, decreased appetite, anxiety, and altered taste. Twenty-seven remedies were prescribed and four of them-, and -were the most frequently used. A high LR was obtained for certain symptoms, which enabled differentiation between the remedies for a given patient.
Homeopathic medicines were associated with improvement in symptoms of COVID-19 cases. Characteristic symptoms of four frequently indicated remedies have been identified using prognostic factor research, findings that can contribute to accurate homeopathic prescribing during future controlled research in COVID-19.
背景/目的：2019冠状病毒病（COVID-19）是一种新型疾病；其临床特征和自然史正在不断演变。顺势疗法实践中每一个记录完善的病例对于决定未来的行动方案都很重要。本研究旨在使用预后因素研究模型确定临床上有用的顺势疗法药物及其用药指征。
这是一项开放标签、多中心的观察性研究，于2020年4月至2020年7月在各公共卫生保健诊所进行。数据是从印度COVID-19综合护理机构的临床实践中前瞻性收集的。使用一组特定标准选择高质量病例。通过计算每种常见症状的似然比（LR）来分析这些病例以阐明预后因素。LR值高（>1）的症状被视为特定药物的用药指征。
在报告的327例COVID-19病例中，211例符合分析的选择标准。最常见的症状是疲劳、喉咙痛、干咳、肌痛、发热、口干和喉咙干、口渴增加、头痛、食欲减退、焦虑和味觉改变。共开出了27种药物，其中4种——和——是最常用的。某些症状获得了较高的LR值，这有助于区分针对特定患者的药物。
顺势疗法药物与COVID-19病例症状的改善有关。通过预后因素研究确定了四种常用药物的特征性症状，这些发现有助于在未来COVID-19的对照研究中进行准确的顺势疗法用药。
