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Is there really a correlation between viral load and olfactory and gustatory dysfunction?

作者信息

Jain Avani, Pandey A K, Kaur Jasleen, Purohit Sandeep

机构信息

Department of ENT, ESIC Medical College and Hospital, Faridabad, India.

Department of Physiology, ESIC Medical College and Hospital, Faridabad, India.

出版信息

Am J Otolaryngol. 2021 Jul-Aug;42(4):103041. doi: 10.1016/j.amjoto.2021.103041. Epub 2021 Apr 16.

DOI:10.1016/j.amjoto.2021.103041
PMID:33931269
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8050396/
Abstract
摘要

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本文引用的文献

1
Objective Sensory Testing Methods Reveal a Higher Prevalence of Olfactory Loss in COVID-19-Positive Patients Compared to Subjective Methods: A Systematic Review and Meta-Analysis.目的：与主观方法相比，客观感觉测试方法显示 COVID-19 阳性患者的嗅觉丧失发生率更高：系统评价和荟萃分析。
Chem Senses. 2020 Dec 5;45(9):865-874. doi: 10.1093/chemse/bjaa064.
2
Acute onset olfactory/taste disorders are associated with a high viral burden in mild or asymptomatic SARS-CoV-2 infections.急性发作的嗅觉/味觉障碍与轻度或无症状 SARS-CoV-2 感染中高病毒载量有关。
Int J Infect Dis. 2020 Oct;99:19-22. doi: 10.1016/j.ijid.2020.07.034. Epub 2020 Jul 26.
3
SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract.SARS-CoV-2 反向遗传学揭示了呼吸道感染的可变梯度。
Cell. 2020 Jul 23;182(2):429-446.e14. doi: 10.1016/j.cell.2020.05.042. Epub 2020 May 27.
4
Presymptomatic SARS-CoV-2 Infections and Transmission in a Skilled Nursing Facility.在一家专业护理机构中出现的 SARS-CoV-2 感染前驱期和传播。
N Engl J Med. 2020 May 28;382(22):2081-2090. doi: 10.1056/NEJMoa2008457. Epub 2020 Apr 24.
5
SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes.严重急性呼吸综合征冠状病毒2（SARS-CoV-2）进入因子与固有免疫基因一起在鼻上皮细胞中高表达。
Nat Med. 2020 May;26(5):681-687. doi: 10.1038/s41591-020-0868-6. Epub 2020 Apr 23.