Department of Bioengineering, University of Pittsburgh School of Engineering, Pittsburgh, Pennsylvania, USA.
Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA; Center for Ultrasound Molecular Imaging and Therapeutics, Department of Medicine, University of Pittsburgh School of Medicine, Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.
Ultrasound Med Biol. 2021 Jul;47(7):1711-1724. doi: 10.1016/j.ultrasmedbio.2021.03.005. Epub 2021 Apr 27.
Thermal strain imaging (TSI) is an ultrasound-based imaging technique intended primarily for diseases in which lipid accumulation is the main biomarker. The goal of the research described here was to successfully implement TSI on a single, commercially available curved linear array transducer for heating and imaging of organs at a deeper depth. For an effective temperature rise of the tissue over a large area, which is key to TSI performance, an innovative multifocus beamforming approach was applied. This yielded a heating area from 32 to 96 mm in the axial direction and -7 to +7 mm in the lateral direction. The pressure fields generated from simulation were in agreement with pressure fields measured with the hydrophone. TSI with safe acoustic power identified with high contrast a rubber inclusion and liposuction fat tissue embedded in a gelatin block.
热应变成像（TSI）是一种基于超声的成像技术，主要用于脂质积累是主要生物标志物的疾病。这里描述的研究目标是成功地在单个商业上可用的弯曲线性阵列换能器上实现 TSI，以加热和成像更深层的器官。为了实现组织的有效温升，这是 TSI 性能的关键，采用了创新的多焦点波束形成方法。这在轴向方向上产生了 32 到 96 毫米的加热区域，在横向方向上产生了-7 到+7 毫米的加热区域。模拟产生的压力场与水听器测量的压力场一致。使用安全声功率的 TSI 以高对比度识别了嵌入明胶块中的橡胶嵌体和抽脂脂肪组织。
