Department of Oncology, University of Cambridge, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Department of Oncology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Br J Cancer. 2021 Oct;125(8):1036-1038. doi: 10.1038/s41416-021-01370-5. Epub 2021 Apr 30.
The advent of ctDNA has the potential to be a game changer in some cancers, but limited data is available in oesophago-gastric cancers (OGC). The prognostic value of ctDNA and the potential for false positive results due to clonal haematopoiesis of indeterminate potential (CHIP) was recently reported in operable OGC.
ctDNA 的出现有可能改变某些癌症的治疗格局,但在食管胃结合部癌(OGC)中可用的数据有限。最近在可手术的 OGC 中报道了 ctDNA 的预后价值和由于不确定的潜在克隆性造血(CHIP)导致假阳性结果的可能性。