Hamadan University of Medical Sciences, School of Medicine, Department of Anesthesiology, Fellowship of Cardiac Anesthesia, Hamadan, Iran.
Hamadan University of Medical Sciences, School of Medicine, Department of Orthopedic Surgery, Hamadan, Iran.
Braz J Anesthesiol. 2021 Sep-Oct;71(5):585-587. doi: 10.1016/j.bjane.2021.04.013. Epub 2021 Apr 28.
Phenylketonuria is a rare disorder that increases the levels of phenylalanine in the blood. As there are scant articles about anesthesia management in phenylketonuria patients, this encouraged us to report a short-time anesthesia management of a child with phenylketonuria for bone fracture. The anesthesia was induced with intravenous ketamine and midazolam. During procedure, he received 100% oxygen via a face mask throughout spontaneous breathing. The operation was uneventful, and he was completely awakened in the recovery room. This report emphasizes that in some situations, the combination of midazolam with ketamine could be used safely for short time anesthesia in phenylketonuria patients.
苯丙酮尿症是一种罕见的疾病,会导致血液中苯丙氨酸水平升高。由于关于苯丙酮尿症患者的麻醉管理的文章很少,这促使我们报告一例苯丙酮尿症儿童骨折的短期麻醉管理。麻醉诱导采用静脉注射氯胺酮和咪达唑仑。在手术过程中,他通过面罩自主呼吸时持续吸入 100%氧气。手术过程顺利,他在恢复室完全清醒。本报告强调,在某些情况下,咪达唑仑与氯胺酮联合使用可安全用于苯丙酮尿症患者的短期麻醉。