Departments of1Neurosurgery and.
2Neuroradiology, Goethe-University, Frankfurt am Main, Germany.
Neurosurg Focus. 2021 May;50(5):E20. doi: 10.3171/2021.2.FOCUS201116.
The aim of this study was to evaluate functional outcome, surgical morbidity, and factors that affect outcomes of surgically treated patients.
The authors retrospectively analyzed patients who underwent microsurgical resection for spinal meningiomas between 2009 and 2020. Patient data and potential variables were collected and evaluated consecutively. Functional outcomes were evaluated using univariate and multivariate analyses.
A total of 119 patients underwent microsurgical resection of spinal meningioma within the study period. After a mean follow-up of 25.4 ± 37.1 months, the rates of overall complication, tumor recurrence, and poor functional outcome were 9.2%, 7.6%, and 5%, respectively. Age, sex, revision surgery, and tumor recurrence were identified as independent predictors of poor functional outcome. Obesity and surgeon's experience had an impact on the complication rate, whereas extent of resection and tumor calcification affected the rate of tumor recurrence.
Microsurgical resection of spinal meningiomas remains safe. Nevertheless, some aspects, such as obesity and experience of the surgeons that result in a higher complication rate and ultimately affect clinical outcome, should be considered when performing surgery.
本研究旨在评估手术治疗患者的功能预后、手术发病率以及影响预后的因素。
作者回顾性分析了 2009 年至 2020 年间接受显微手术切除的脊髓脊膜瘤患者。连续收集患者资料和潜在变量,并进行评估。采用单因素和多因素分析评估功能预后。
研究期间,共有 119 例患者接受了脊髓脊膜瘤的显微手术切除。平均随访 25.4±37.1 个月后,总并发症、肿瘤复发和功能预后不良的发生率分别为 9.2%、7.6%和 5%。年龄、性别、翻修手术和肿瘤复发是功能预后不良的独立预测因素。肥胖和术者经验对并发症发生率有影响,而切除程度和肿瘤钙化则影响肿瘤复发率。
脊髓脊膜瘤的显微切除术仍然安全。然而,在进行手术时,应考虑一些方面,如肥胖和术者的经验,这些因素会导致更高的并发症发生率,并最终影响临床预后。