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3 种经椎间盘固定植入物治疗 L5/S1 脊柱滑脱症的生物力学比较。

Biomechanical comparison of 3 types of transdiscal fixation implants for fixing high-grade L5/S1 spine spondylolisthesis.

机构信息

London Health Science Centre, Victoria Hospital, London, N6A 5W9, Canada; Dept. of Surgery (Div. of Orthopaedic Surgery), Western University, London, N6A 3K7, Canada; Dept. of Trauma and Orthopaedics, Gloucestershire Hospitals NHS Foundation Trust, GL53 7AN, Gloucestershire, UK.

London Health Science Centre, Victoria Hospital, London, N6A 5W9, Canada.

出版信息

Spine J. 2021 Sep;21(9):1587-1593. doi: 10.1016/j.spinee.2021.04.017. Epub 2021 Apr 30.

Abstract

BACKGROUND CONTEXT

There are several options for the stabilization of high-grade lumbosacral spondylolisthesis including transdiscal screws, the Bohlman technique (transdiscal fibular strut) and the modified Bohlman technique (transdiscal titanium mesh cage). The choice of an optimum construct remains controversial; therefore, we endeavoured to study and compare the biomechanical performance of these 3 techniques.

PURPOSE

The aim of this study was to compare 3 types of transdiscal fixation biomechanically in an in vitro porcine lumbar-sacral spine model.

STUDY DESIGN/SETTING: Porcine cadaveric biomechanical study.

METHODS

18 complete lumbar-sacral porcine spines were split into 3 repair groups, transdiscal screws (TS), Bohlman technique, and a modified Bohlman technique (MBT). Range of motion (L3 - S1) was measured in an intact and repaired state for flexion, extension, left/right lateral bending, and left/right torsion. To recreate a high-grade lumbosacral spondylolisthesis a bilateral L5/S1 facetectomy, removing the intervertebral disc completely, and the L5 body was displaced 50%-60% over the sacral promontory. Results were analyzed and compared to intact baseline measurements. Standard quasi-static moments (5 Nm) were applied in all modes.

RESULTS

All range of motion (ROM) were in reference to intact baseline values. TS had the lowest ROM in all modes (p=.006-.495). Statistical difference was found only in extension for TS vs. BT (p=.011) and TS vs. MBT (p=.014). No bone or implant failures occurred.

CONCLUSION

TS provided the lowest ROM in all modes of loading compared to Bohlman technique and MBT. Our study indicates that TS results in the most biomechanically stable construct.

CLINICAL SIGNIFICANCE

Knowledge of the biomechanical attributes of various constructs could aid physicians in choosing a surgical construct for their patients.

摘要

背景

对于高等级腰骶椎滑脱的稳定,有几种选择,包括经椎间盘螺钉、Bohlman 技术(经椎间盘腓骨支柱)和改良 Bohlman 技术(经椎间盘钛网笼)。最佳构建物的选择仍然存在争议;因此,我们努力研究和比较这 3 种技术的生物力学性能。

目的

本研究旨在比较经椎间盘固定 3 种类型在体外猪腰椎-骶椎模型中的生物力学性能。

研究设计/设置:猪尸体生物力学研究。

方法

将 18 个完整的腰椎-骶椎猪脊柱分为 3 个修复组,经椎间盘螺钉(TS)、Bohlman 技术和改良 Bohlman 技术(MBT)。在完整和修复状态下测量 L3-S1 节段的运动范围(ROM),用于屈伸、左右侧屈和左右扭转。为了重建高等级腰骶椎滑脱,双侧 L5/S1 关节突切除术,完全切除椎间盘,并将 L5 体向骶骨岬移位 50%-60%。结果与完整的基线测量值进行了分析和比较。在所有模式下均施加标准准静态力矩(5 Nm)。

结果

所有运动范围(ROM)均与完整的基线值相对应。在所有模式下,TS 的 ROM 最低(p=.006-.495)。仅在 TS 与 BT(p=.011)和 TS 与 MBT(p=.014)的伸展模式下发现统计学差异。没有发生骨或植入物失败。

结论

与 Bohlman 技术和 MBT 相比,TS 在所有加载模式下的 ROM 最低。我们的研究表明,TS 导致最具生物力学稳定性的构建。

临床意义

了解各种构建物的生物力学特性可以帮助医生为患者选择手术构建物。

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