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中国武汉不同食物中高氯酸盐的膳食暴露与风险评估。

Dietary exposure and risk assessment of perchlorate in diverse food from Wuhan, China.

机构信息

Key Laboratory for Deep Processing of Major Grain and Oil of Ministry of Education, Wuhan Polytechnic University, Wuhan, Hubei 430023, China.

HC Key Laboratory of Food Safety Risk Assessment, Food Safety Research Unit (2019RU014) of Chinese Academy of Medical Science, China National Center for Food Safety Risk Assessment, Beijing 100021, China.

出版信息

Food Chem. 2021 Oct 1;358:129881. doi: 10.1016/j.foodchem.2021.129881. Epub 2021 Apr 20.

DOI:10.1016/j.foodchem.2021.129881
PMID:33933950
Abstract

The perchlorate levels in 330 foods belonging to 5 varieties obtained from Wuhan were monitored. An ultra-high performance liquid chromatography coupled with triple quadrupoles mass spectrometry in combination with ClO internal standard method was performed to determine the level of perchlorate in various foods. Hereafter, dietary exposure and risk assessment of perchlorate was evaluated. The results revealed that the average level of perchlorate was 15.04 µg/kg with a detection of 95% among the whole food groups. The level of perchlorate in vegetables was the highest among the 5 varieties of food with an average content of 27.39 µg/kg, which in meat was the lowest with an average of 3.65 µg/kg. Estimated dietary intake results illustrated that males showed exposure in the range 0.004-0.18 µg/kg bw/day, which for females was 0.01-0.21 µg/kg bw/day. The results indicated that exposure to perchlorate via the food consumption for Wuhan people was evaluated as safe.

摘要

对武汉地区 5 个品种的 330 种食品中的高氯酸盐含量进行了监测。采用超高效液相色谱-三重四级杆质谱联用 ClO 内标法测定了各种食品中的高氯酸盐含量。在此基础上,对高氯酸盐的膳食暴露和风险进行了评估。结果表明,在所检测的全部食品组中,高氯酸盐的平均含量为 15.04μg/kg,检出率为 95%。5 种食品中,高氯酸盐在蔬菜中的含量最高,平均含量为 27.39μg/kg,在肉类中的含量最低,平均含量为 3.65μg/kg。膳食摄入量估算结果表明,男性的暴露量在 0.004-0.18μg/kg bw/day 之间,女性为 0.01-0.21μg/kg bw/day。结果表明,武汉居民通过食物摄入高氯酸盐的暴露水平被评估为安全。

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