Phase angle association with metabolic profile in adults: A population-based study.

OBJECTIVE

This study assesses the association of the phase angle (PhA) with the metabolic profile in adults of both sexes.

METHODS

This is a cross-sectional, population-based study including 949 adults 20 to 59 y of age living in the Viçosa, Minas Gerais, Brazil - urban zone. The PhA was measured based on electrical bioimpedance analysis. The metabolic profile comprised the following components: waist circumference, glucose, high-density lipoprotein cholesterol (HDL-C), non-HDL-C, triglycerides, C-reactive protein, homeostatic model assessment index-insulin resistance (HOMA-IR), serum uric acid, systolic blood pressure, and diastolic blood pressure. Linear regression models (crude and adjusted) were used to determine the association between each independent and dependent variable; statistical significance was analyzed at 5%.

RESULTS

Multiple analyses showed that the increase in the values of waist circumference (β: -0.01; 95%CI: -0.03; -0.01) represented lower values in the PhA. For the glucose, non-HDL-C, triglycerides, CRP, HOMA-IR and uric acid there was no association with PhA in the adjusted models. .

CONCLUSION

Low PhA was directly associated with grater values of the waist circumference, even after adjustments were made in the sociodemographic, lifestyle variables and body mass index; this outcome suggests that PhA is a promising cardiometabolic profile biomarker in adults.