Frappat P, François P, Baccard C
Unité de réanimation infantile, CHU Grenoble, France.
Pediatrie. 1988;43(2):161-4.
The authors report 6 cases of acute encephalopathy during the course of primary rubella infection. The mean age of the patients was 7 years and 6 months. Clinical features included, 3 days after an inconstant exanthema, seizures, coma and hyperthermia. The diagnosis of rubella was confirmed by a high rate of antibodies in serum with presence of IgM fraction. Five children recovered fully, one patient remained epileptic. The authors discuss the problems of diagnosis, the nosological position and the treatment of non-congenital rubella encephalitis.
作者报告了6例原发性风疹感染过程中出现急性脑病的病例。患者的平均年龄为7岁6个月。临床特征包括,在出现不恒定皮疹3天后,出现癫痫发作、昏迷和高热。血清中抗体率高且存在IgM成分,证实为风疹。5名儿童完全康复,1名患者仍患有癫痫。作者讨论了非先天性风疹脑炎的诊断问题、疾病分类地位和治疗方法。