Edinburgh Orthopaedics, The Royal Infirmary of Edinburgh, Edinburgh, UK.
Department of Orthopaedics, University of Edinburgh, Edinburgh, UK.
Bone Joint J. 2021 May;103-B(5):846-854. doi: 10.1302/0301-620X.103B5.BJJ-2020-0396.R1.
The aim of this study was to identify the minimal clinically important difference (MCID), minimal important change (MIC), minimal detectable change (MDC), and patient-acceptable symptom state (PASS) threshold in the Forgotten Joint Score (FJS) according to patient satisfaction six months following total knee arthroplasty (TKA).
During a one-year period 484 patients underwent a primary TKA and completed preoperative and six-month FJS and OKS. At six months patients were asked, "How satisfied are you with your operated knee?" Their response was recorded as: very satisfied, satisfied, neutral, dissatisfied, or very dissatisfied. The difference between patients recording neutral (n = 44) and satisfied (n = 153) was used to define the MCID. MIC for a cohort was defined as the change in the FJS for those patients declaring their outcome as satisfied, whereas receiver operating characteristic curve analysis was used to determine the MIC for an individual and the PASS threshold. Distribution-based methodology was used to calculate the MDC.
Using satisfaction as the anchor question, the MCID for the FJS was 16.6 (95% confidence interval (CIs) 8.9 to 24.3; p < 0.001) and when adjusting for confounding this decreased to 13.7 points (95% CI 4.8 to 22.5; p < 0.001). The MIC for the FJS for a cohort of patients was 17.7 points and for an individual patient was 10 points. The MDC90 for the FGS was 12 points; where 90% of patients scoring more than this will have experienced a real change that is beyond measurement error. The PASS was defined as 22 points or more in the postoperative FJS.
The estimates for MCID and MIC can be used to assess whether there is clinical difference between two groups and whether a cohort/patient has had a meaningful change in their FJS, respectively. The MDC90 of 12 points suggests a value lower than this may fall within measurement error. A postoperative FJS of 22 or more was predictive of achieving PASS. Cite this article: 2021;103-B(5):846-854.
本研究旨在确定全膝关节置换术(TKA)后 6 个月患者满意度的情况下,遗忘关节评分(FJS)的最小临床重要差异(MCID)、最小有意义变化(MIC)、最小可检测变化(MDC)和患者可接受的症状状态(PASS)阈值。
在为期一年的时间内,484 例患者接受了初次 TKA,并在术前和 6 个月时完成了 FJS 和 OKS 评估。在 6 个月时,患者被问到:“您对手术膝关节的满意度如何?”他们的回答记录为:非常满意、满意、中立、不满意或非常不满意。将记录为中立(n=44)和满意(n=153)的患者之间的差异定义为 MCID。对于一个队列的 MIC 定义为那些报告结果满意的患者的 FJS 变化,而接受者操作特征曲线分析用于确定个体的 MIC 和 PASS 阈值。基于分布的方法用于计算 MDC。
使用满意度作为锚定问题,FJS 的 MCID 为 16.6(95%置信区间(CI)8.9 至 24.3;p<0.001),当调整混杂因素后,这一数值降至 13.7 分(95%CI 4.8 至 22.5;p<0.001)。队列患者的 FJS MIC 为 17.7 分,个体患者的 MIC 为 10 分。FGS 的 MDC90 为 12 分;得分高于此值的 90%患者将经历超出测量误差的真实变化。PASS 定义为术后 FJS 评分 22 分或以上。
MCID 和 MIC 的估计值可用于评估两组之间是否存在临床差异,以及队列/患者的 FJS 是否发生了有意义的变化。90%的 MDC90 为 12 分,表明低于此值的分数可能存在于测量误差内。术后 FJS 评分达到 22 分或更高可预测达到 PASS。