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病例报告:老年人用药管理的复杂性及停用抗胆碱能药物的重要性。

Case Report: The Complexities of Managing Medications and the Importance of Deprescribing Anticholinergics in Older Adults.

作者信息

Elliott Taylor, Eckmann Lynne, Moga Daniela C

机构信息

Department of Pharmacy Practice and Science, College of Pharmacy, University of Kentucky, Lexington, KY, United States.

PRO2RX LLC Pharmacy Consulting Services, Lexington, KY, United States.

出版信息

Front Pharmacol. 2021 Apr 16;12:584667. doi: 10.3389/fphar.2021.584667. eCollection 2021.

DOI:10.3389/fphar.2021.584667
PMID:33935693
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8087073/
Abstract

Potentially inappropriate anticholinergic medications (including over-the-counter products), polypharmacy, and the existence of communication barriers among members of the interprofessional team frequently contribute to clinical complexity in older adults. We present the case of a frail 86-year old female from the perspective of a community pharmacist managing outpatient medications and transitions of care. CD's past medical history is significant for dementia, multiple falls, recurrent urinary tract infections, depression, cardiac arrhythmia, macular degeneration, chronic pain, depression, and cerebrovascular disease.

摘要

潜在不适当的抗胆碱能药物(包括非处方产品)、多重用药以及跨专业团队成员之间存在沟通障碍,这些因素常常导致老年人临床情况复杂化。我们从一名管理门诊用药和护理转接的社区药剂师的角度,介绍一位体弱的86岁女性的病例。CD的既往病史包括痴呆、多次跌倒、复发性尿路感染、抑郁症、心律失常、黄斑变性、慢性疼痛、抑郁症和脑血管疾病。

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American Geriatrics Society 2019 Updated AGS Beers Criteria® for Potentially Inappropriate Medication Use in Older Adults.美国老年医学学会 2019 年更新的老年人潜在不适当药物使用 AGS Beers 标准®。
J Am Geriatr Soc. 2019 Apr;67(4):674-694. doi: 10.1111/jgs.15767. Epub 2019 Jan 29.
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老年门诊患者抗胆碱能负担及其危险因素评估。
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2023 Jan 28;48(1):114-122. doi: 10.11817/j.issn.1672-7347.2023.220080.
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Over-the-counter medications containing diphenhydramine and doxylamine used by older adults to improve sleep, a Letter.一篇信函:老年人使用含苯海拉明和多西拉敏的非处方药来改善睡眠。
Int J Clin Pharm. 2017 Aug;39(4):627-628. doi: 10.1007/s11096-017-0500-0. Epub 2017 Jun 15.
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