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新生期给予睾酮,但并非在子宫内与雄性相邻,可增强经睾酮处理的成年雌性小鼠的雄性性行为表现。

Neonatal testosterone administration, but not in utero contiguity to males, augments the display of male sexual behavior by testosterone-treated adult female mice.

作者信息

Gandelman R, Kozak M

机构信息

Department of Psychology, Rutgers University, New Brunswick, NJ 08903.

出版信息

Physiol Behav. 1988;42(5):453-6. doi: 10.1016/0031-9384(88)90175-8.

DOI:10.1016/0031-9384(88)90175-8
PMID:3393605
Abstract

Male copulatory behavior of adult female mice given slow-release capsules of testosterone was examined in animals that developed in utero contiguous to two males (mFm) or to two females (fFf). Other females of unspecified uterine position which were injected with testosterone propionate on the day of birth as well as intact males also were examined. mFm and fFf females did not differ on any measure; latency to the first mount, number of mount bouts, number of mount bouts with genital thrusting. The perinatally androgenized females exhibited more mount bouts and more bouts accompanied by genital thrusting than did mFm and fFf subjects. The former also displayed more mount bouts with thrusting on the second pair of tests than males. Lastly, a greater proportion of perinatally androgenized females than mFm or fFf animals displayed male sexual behavior two weeks following removal of the testosterone-containing capsule.

摘要

对给予睾酮缓释胶囊的成年雌性小鼠的交配行为进行了检查,这些动物在子宫内与两只雄性(mFm)或两只雌性(fFf)相邻发育。还检查了出生当天注射丙酸睾酮的子宫位置未明确的其他雌性以及完整雄性。mFm和fFf雌性在任何测量指标上均无差异;首次爬跨潜伏期、爬跨回合数、伴有生殖器 thrusting 的爬跨回合数。围产期雄激素化的雌性比mFm和fFf个体表现出更多的爬跨回合以及更多伴有生殖器 thrusting 的回合。前者在第二轮测试中也比雄性表现出更多伴有 thrusting 的爬跨回合。最后,在移除含睾酮胶囊两周后,围产期雄激素化的雌性比mFm或fFf动物表现出雄性性行为的比例更高。 (注:原文中“genital thrusting”可能存在特定医学术语含义,这里按字面翻译,不太明确其准确意思)

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