Glazer G M, Orringer M B, Chenevert T L, Borrello J A, Penner M W, Quint L E, Li K C, Aisen A M
Department of Radiology, University of Michigan Medical Center, Ann Arbor 48109.
Radiology. 1988 Aug;168(2):429-31. doi: 10.1148/radiology.168.2.3393661.
The authors measured the T1 and T2 relaxation times of freshly excised human mediastinal lymph nodes to determine whether the times are clinically useful in distinguishing benign from malignant nodes. All measurements were performed at 20 MHz and 40 degrees C, within 45 minutes of lymph node excision. Mean T1 and T2 relaxation times of 99 benign nodes were 566 msec (standard deviation [SD], 117 msec) and 92 msec (SD, 29 msec), respectively. For the 16 malignant nodes, these times were 640 msec (SD, 138 msec) and 105 msec (SD, 26 msec), respectively (P less than .05 for difference in T1 times, P greater than .05 for difference in T2 times). Histograms showed considerable overlap in the relaxation times of benign and malignant nodes such that absolute measurement of these times will likely be of limited clinical value.
作者测量了新鲜切除的人纵隔淋巴结的T1和T2弛豫时间，以确定这些时间在临床上区分良性和恶性淋巴结是否有用。所有测量均在淋巴结切除后45分钟内，于20兆赫和40摄氏度下进行。99个良性淋巴结的平均T1和T2弛豫时间分别为566毫秒（标准差[SD]，117毫秒）和92毫秒（SD，29毫秒）。对于16个恶性淋巴结，这些时间分别为640毫秒（SD，138毫秒）和105毫秒（SD，26毫秒）（T1时间差异P小于0.05，T2时间差异P大于0.05）。直方图显示良性和恶性淋巴结的弛豫时间有相当大的重叠，因此这些时间的绝对测量可能临床价值有限。
