Barbara Zachary, Ellenwood Savannah P, Loe Emily D, Choi Joon, Ryan Kathleen, Joseph Nancy
University of Florida Shands Children's Hospital, Department of Pediatrics, Gainesville, FL, USA.
University of Florida, School of Medicine, Gainesville, FL, USA.
Case Rep Pediatr. 2021 Apr 2;2021:5584514. doi: 10.1155/2021/5584514. eCollection 2021.
Kawasaki disease is a medium vessel vasculitis with a multisystem presentation affecting 9-20 per 100,000 children under 5 years of age in the United States. coinfection has not been previously described. We present a 12-month-old vaccinated male with Kawasaki disease in the setting of bacteremia. Initial intervention for the Kawasaki disease with IVIG was ineffective, prompting adjunctive therapy with anakinra, with eventual full recovery. Concurrent Kawasaki disease and bacteremia may confound diagnosis and necessitate nontraditional treatment approaches.
川崎病是一种累及中等血管的血管炎,可有多系统表现,在美国每10万名5岁以下儿童中,有9至20人受其影响。此前尚未有关于合并感染的描述。我们报告了一名12个月大的接种过疫苗的男性,在发生菌血症的情况下患了川崎病。最初用静脉注射免疫球蛋白对川崎病进行干预无效,于是加用阿那白滞素进行辅助治疗,最终实现了完全康复。川崎病与菌血症同时存在可能会使诊断变得复杂,需要采用非传统的治疗方法。