Boppana Sri Harsha, Dulla Nageswara R, Beutler Bryce D, Pitani Sujatha, Kaur Ratinder
Internal Medicine, University of Nevada Reno School of Medicine, Reno, USA.
Internal Medicine, Mythri Multispecialty Hospital, Guntur, IND.
Cureus. 2021 Mar 30;13(3):e14197. doi: 10.7759/cureus.14197.
Polyarteritis nodosa (PAN) is a rare multisystem vasculopathy that predominantly affects medium-sized arteries. Involvement of the cardiac and/or pulmonary vasculature may be fatal. We describe a 67-year-old Japanese male who presented with multiple coronary artery aneurysms and subsequently developed lower extremity gangrene. A diagnosis of PAN was established based on the correlation of clinical presentation and laboratory and imaging findings. In addition, we review other manifestations of PAN and differential considerations for this rare but potentially lethal condition.
结节性多动脉炎(PAN)是一种罕见的多系统血管病,主要累及中等大小动脉。心脏和/或肺血管受累可能是致命的。我们描述了一名67岁的日本男性,他出现多发性冠状动脉瘤,随后发展为下肢坏疽。根据临床表现与实验室及影像学检查结果的相关性确诊为PAN。此外,我们还回顾了PAN的其他表现以及对这种罕见但可能致命疾病的鉴别诊断要点。