Wang S, He S, Zhang X, Sun J, Huang Q, Liu J, Han C, Yin Z, Ding B, Yin J
The Department of Breast Oncoplastic Surgery, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China.
National Clinical Research Center for Cancer, Tianjin, China.
JPRAS Open. 2021 Mar 27;29:1-9. doi: 10.1016/j.jpra.2021.03.005. eCollection 2021 Sep.
Acellular Bovine Pericardium Matrix (ABPM) is a new material in implant-based breast reconstruction (IBBR). Few studies have reported on its outcome and complications worldwide and most studies were without a control group. Our aim was to compare its use in IBBR with the other two conventional implant-based reconstruction methods.
A retrospective review of patients undergoing IBBR from January to December 2018 was performed. Patients were assigned to the ABPM-assisted IBBR (group A), latissimus dorsi-assisted IBBR (group B) and two-stage IBBR (group C). Patients' post-operative complications, cost-effectiveness and Quality of Life were compared.
100 patients with 100 breasts were included in the study. No complications occurred in group C ( = 11). No significant differences were noted between group A ( = 44) and group B ( = 45) in terms of overall complications (9.1% vs 11.1%, = 0.973). Group B had the longest operative duration (310.8 ± 62.3 min, <0.001). The cost of hospitalization forthe three groups was $8051.3 ± 849.2, $7566.0 ± 1172.7 and $7896.5 ± 1762.2, respectively ( = 0.128). The postoperative Breast-Q scores were similar across the three groups.
ABPM demonstrated acceptable complication rates, cost-effectiveness and quality of life outcomes when compared to LD-assisted IBBR and two-stage IBBR.
脱细胞牛心包基质(ABPM)是基于植入物的乳房重建(IBBR)中的一种新材料。全球范围内很少有研究报道其效果和并发症,并且大多数研究没有对照组。我们的目的是比较其在IBBR中的应用与其他两种传统的基于植入物的重建方法。
对2018年1月至12月接受IBBR的患者进行回顾性研究。患者被分为ABPM辅助的IBBR组(A组)、背阔肌辅助的IBBR组(B组)和两阶段IBBR组(C组)。比较患者术后并发症、成本效益和生活质量。
该研究纳入了100例患者的100个乳房。C组(n = 11)未发生并发症。A组(n = 44)和B组(n = 45)在总体并发症方面无显著差异(9.1%对11.1%,P = 0.973)。B组手术时间最长(310.8 ± 62.3分钟,P < 0.001)。三组的住院费用分别为8051.3 ± 849.2美元、7566.0 ± 1172.7美元和7896.5 ± 1762.2美元(P = 0.128)。三组术后的乳房Q评分相似。
与背阔肌辅助的IBBR和两阶段IBBR相比,ABPM的并发症发生率、成本效益和生活质量结果均可接受。