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与传统的基于植入物的乳房重建相比,脱细胞牛心包基质在即刻乳房重建中的应用

Acellular bovine pericardium matrix in immediate breast reconstruction compared with conventional implant-based breast reconstruction.

作者信息

Wang S, He S, Zhang X, Sun J, Huang Q, Liu J, Han C, Yin Z, Ding B, Yin J

机构信息

The Department of Breast Oncoplastic Surgery, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China.

National Clinical Research Center for Cancer, Tianjin, China.

出版信息

JPRAS Open. 2021 Mar 27;29:1-9. doi: 10.1016/j.jpra.2021.03.005. eCollection 2021 Sep.

Abstract

BACKGROUND

Acellular Bovine Pericardium Matrix (ABPM) is a new material in implant-based breast reconstruction (IBBR). Few studies have reported on its outcome and complications worldwide and most studies were without a control group. Our aim was to compare its use in IBBR with the other two conventional implant-based reconstruction methods.

METHODS

A retrospective review of patients undergoing IBBR from January to December 2018 was performed. Patients were assigned to the ABPM-assisted IBBR (group A), latissimus dorsi-assisted IBBR (group B) and two-stage IBBR (group C). Patients' post-operative complications, cost-effectiveness and Quality of Life were compared.

RESULTS

100 patients with 100 breasts were included in the study. No complications occurred in group C ( = 11). No significant differences were noted between group A ( = 44) and group B ( = 45) in terms of overall complications (9.1% vs 11.1%,  = 0.973). Group B had the longest operative duration (310.8 ± 62.3 min, <0.001). The cost of hospitalization forthe three groups was $8051.3 ± 849.2, $7566.0 ± 1172.7 and $7896.5 ± 1762.2, respectively ( = 0.128). The postoperative Breast-Q scores  were similar across the three groups.

CONCLUSIONS

ABPM demonstrated acceptable complication rates, cost-effectiveness and quality of life outcomes when compared to LD-assisted IBBR and two-stage IBBR.

摘要

背景

脱细胞牛心包基质(ABPM)是基于植入物的乳房重建(IBBR)中的一种新材料。全球范围内很少有研究报道其效果和并发症,并且大多数研究没有对照组。我们的目的是比较其在IBBR中的应用与其他两种传统的基于植入物的重建方法。

方法

对2018年1月至12月接受IBBR的患者进行回顾性研究。患者被分为ABPM辅助的IBBR组(A组)、背阔肌辅助的IBBR组(B组)和两阶段IBBR组(C组)。比较患者术后并发症、成本效益和生活质量。

结果

该研究纳入了100例患者的100个乳房。C组(n = 11)未发生并发症。A组(n = 44)和B组(n = 45)在总体并发症方面无显著差异(9.1%对11.1%,P = 0.973)。B组手术时间最长(310.8 ± 62.3分钟,P < 0.001)。三组的住院费用分别为8051.3 ± 849.2美元、7566.0 ± 1172.7美元和7896.5 ± 1762.2美元(P = 0.128)。三组术后的乳房Q评分相似。

结论

与背阔肌辅助的IBBR和两阶段IBBR相比,ABPM的并发症发生率、成本效益和生活质量结果均可接受。

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