Uzunay Hüseyin, Selvi Fatih, Bedel Cihan, Karakoyun Omer Faruk
Department of Emergency Medicine, Kas State Hospital, Antalya, Turkey.
Department of Emergency Medicine, Health Science University, Antalya Training and Research Hospital, Antalya, Turkey.
SN Compr Clin Med. 2021;3(8):1717-1721. doi: 10.1007/s42399-021-00935-y. Epub 2021 Apr 27.
Capnography is the non-invasive measurement and graphic representation of the partial pressure of CO2 in expiration. Although there are many studies in the literature comparing the partial pressure of carbon dioxide (pCO2) and end-tidal CO2 (ETCO2) values in patients who underwent IMV (invasive mechanical ventilation), there are no studies showing their interchangeable applicability in patients who received NIMV (non-IMV). We aimed to evaluate whether the use of ETCO2 in the treatment process can replace pCO2 use in patients scheduled for NIMV treatment in the emergency department. Patients who applied to the emergency department with respiratory distress between March 2019 and January 2020, who were diagnosed with acute cardiogenic edema or acute chronic obstructive pulmonary disease (COPD) exacerbation, and who needed NIMV were included in the study. General characteristics of the patients and the pCO2 and ETCO2 values were measured in the blood gas 1 h after the NIMV application was started. 64.2% (99 patients) of the patients included in the study were male, and 35.8% (55 patients) were female. The mean age of the patients included in the study was 69.1 ± 12.2 years. The mean pCO2 values were measured as 52.6 ± 13.2. The mean of ETCO2 values measured simultaneously was 33.6 ± 10.1. There was a significant difference between the controlled pCO2 values and ETCO2 values at the first hour of NIMV treatment (Z: - 10.640, < 0.001). The ETCO2 level was found to be different in our patients who received NIMV treatment, which could not be used instead of the pCO2 level.
二氧化碳描记法是对呼气中二氧化碳分压进行无创测量并以图形表示。尽管文献中有许多研究比较了接受有创机械通气(IMV)患者的二氧化碳分压(pCO2)和呼气末二氧化碳分压(ETCO2)值,但尚无研究表明它们在接受无创机械通气(NIMV)的患者中可互换使用。我们旨在评估在急诊科计划接受NIMV治疗的患者中,治疗过程中使用ETCO2是否可以替代pCO2。纳入研究的患者为2019年3月至2020年1月因呼吸窘迫就诊于急诊科,被诊断为急性心源性肺水肿或急性慢性阻塞性肺疾病(COPD)加重且需要NIMV的患者。在开始NIMV治疗1小时后,测量患者的一般特征以及血气中的pCO2和ETCO2值。纳入研究的患者中64.2%(99例)为男性,35.8%(55例)为女性。纳入研究患者的平均年龄为69.1±12.2岁。pCO2平均值测量为52.6±13.2。同时测量的ETCO2平均值为33.6±10.1。在NIMV治疗的第一小时,对照的pCO2值和ETCO2值之间存在显著差异(Z:-10.640,P<0.001)。我们发现接受NIMV治疗的患者的ETCO2水平不同,不能替代pCO2水平。