Department of Pediatric Allergy, Baskent University, Izmir, Turkey;
Department of Psychiatry, Baskent University, Izmir, Turkey.
Allergol Immunopathol (Madr). 2021 May 1;49(3):138-145. doi: 10.15586/aei.v49i3.196. eCollection 2021.
Long-term inhaled corticosteroid (ICS) use in children with asthma causes serious concerns in parents, leading to treatment non-adherence. This study aimed to investigate the effect of maternal anxiety and attitudes on adherence to ICS therapy in children with asthma.
The patient group included the children with mild to moderate persistent asthma, aged 6-11 years. Healthy children in a similar age range were included as a control group. The patient group was divided into two categories (treatment adherent and non-adherent) according to the regularity of ICS use. All patients were assessed with Childhood-Asthma Control Test (C-ACT), and their mothers were assessed using Parent Attitude Research Instrument (PARI) and Beck's Anxiety Inventory (BAI).
A total of 156 children (age: 7.4 ± 1.4 years, F/M: 71/85) with persistent asthma and 60 healthy children (age: 7.5 ± 1.3 years, F/M:25/35) were included in the study. The rate of adherence in children with asthma was 52.6%. Mothers of non-adherent patients had significantly higher BAI scores than those of the adherent patients and controls (p < 0.001 and p < 0.001, respectively). The number of mothers who indicated that they did not have enough information about asthma and treatment was also higher in the non-adherent group. PARI subtest scores were not different between the adherent and non-adherent groups.
In our study, it was found that mothers' anxiety levels and their knowledge about asthma and medications were associated with treatment adherence in children with asthma. Psychological and educational support to the families of children with asthma would improve their treatment adherence and efficacy.
儿童哮喘长期吸入皮质类固醇（ICS）会引起家长的严重担忧，导致治疗不依从。本研究旨在探讨母亲焦虑和态度对哮喘儿童ICS 治疗依从性的影响。
患者组包括 6-11 岁轻至中度持续性哮喘儿童。选择年龄相近的健康儿童作为对照组。根据 ICS 使用的规律性，将患者组分为治疗依从组和非依从组。所有患者均采用儿童哮喘控制测试（C-ACT）进行评估，其母亲采用家长态度研究工具（PARI）和贝克焦虑量表（BAI）进行评估。
共纳入 156 例持续性哮喘儿童（年龄：7.4±1.4 岁，男/女：71/85）和 60 例健康儿童（年龄：7.5±1.3 岁，男/女：25/35）。哮喘儿童的依从率为 52.6%。不依从患儿的母亲 BAI 评分明显高于依从患儿和对照组（均 P<0.001）。不依从组中表示对哮喘和治疗了解不够的母亲人数也更多。依从组和不依从组的 PARI 子量表评分无差异。
在本研究中，我们发现母亲的焦虑水平及其对哮喘和药物的了解与哮喘儿童的治疗依从性有关。对哮喘患儿家庭进行心理和教育支持将提高其治疗依从性和疗效。
