Cardiology Division Department of Medicine Massachusetts General HospitalHarvard Medical School Boston MA.
Saint Luke's Mid America Heart Institute Kansas City MO.
J Am Heart Assoc. 2021 May 18;10(10):e021350. doi: 10.1161/JAHA.120.021350. Epub 2021 May 3.
Background Data on hospital variation in 30-day readmission rates after transcatheter aortic valve replacement (TAVR) are limited. Further, whether such variation is explained by differences in hospital characteristics and hospital practice patterns remains unknown. Methods and Results We used the 2017 Nationwide Readmissions Database to identify hospitals that performed at least 5 TAVRs. Hierarchical logistic regression models were used to examine between-hospital variation in 30-day all-cause risk-standardized readmission rate (RSRR) after TAVR and to explore reasons underlying hospital variation in 30-day RSRR. The study included 27 091 index TAVRs performed across 325 hospitals. The median (interquartile range) hospital-level 30-day RSRR was 11.9% (11.1%-12.8%) ranging from 8.8% to 16.5%. After adjusting for differences in patient characteristics, there was significant between-hospital variation in 30-day RSRR (hospital odds ratio, 1.59; 95% CI, 1.39-1.77). Differences in length of stay and discharge disposition accounted for 15% of the between-hospital variance in RSRRs. There was no significant association between hospital characteristics and 30-day readmission rates after TAVR. There was statistically significant but weak correlation between 30-day RSRR after TAVR and that after surgical aortic valve replacement, percutaneous coronary intervention, acute myocardial infarction, heart failure, and pneumonia (=0.132-0.298; <0.001 for all). Causes of 30-day readmission varied across hospitals, with noncardiac readmissions being more common at the bottom 5% hospitals (ie, those with the highest RSRRs). Conclusions There is significant variation in 30-day RSRR after TAVR across hospitals that is not entirely explained by differences in patient or hospital characteristics as well as hospital-wide practice patterns. Noncardiac readmissions are more common in hospitals with the highest RSRRs.
背景 经导管主动脉瓣置换术(TAVR)后 30 天再入院率的医院间差异数据有限。此外,医院特征和医院实践模式的差异是否能解释这种差异仍不清楚。
方法和结果 我们使用 2017 年全国再入院数据库确定了至少进行 5 例 TAVR 的医院。使用分层逻辑回归模型来检查 TAVR 后 30 天全因风险标准化再入院率(RSRR)的医院间差异,并探讨导致 30 天 RSRR 医院间差异的原因。该研究纳入了在 325 家医院进行的 27091 例 TAVR 指数。中位(四分位间距)医院水平 30 天 RSRR 为 11.9%(11.1%-12.8%),范围为 8.8%-16.5%。在调整了患者特征的差异后,30 天 RSRR 仍存在显著的医院间差异(医院比值比,1.59;95%置信区间,1.39-1.77)。住院时间和出院安置的差异占 RSRR 医院间差异的 15%。医院特征与 TAVR 后 30 天再入院率之间无显著相关性。TAVR 后 30 天 RSRR 与外科主动脉瓣置换术、经皮冠状动脉介入治疗、急性心肌梗死、心力衰竭和肺炎后 30 天 RSRR 之间存在统计学上显著但微弱的相关性(=0.132-0.298;所有均<0.001)。不同医院的 30 天再入院原因不同,非心脏原因再入院在 RSRR 最高的前 5%的医院(即 RSRR 最高的医院)更为常见。
结论 TAVR 后 30 天 RSRR 存在显著的医院间差异,这种差异不能完全用患者或医院特征以及医院范围内的实践模式的差异来解释。非心脏原因再入院在 RSRR 最高的医院更为常见。