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新生儿自发性肺动脉血栓形成。

Spontaneous pulmonary artery thrombus in a neonate.

作者信息

Shrimanth Y S, Prasad Krishna, Karthik Adari Appala, Barwad Parag, Pruthvi C R, Gawalkar Atit A, Santosh Krishna, Naganur Sanjeev

机构信息

Department of Cardiology, Advanced Cardiac Centre, Post Graduate Institute for Medical Education and Research (PGIMER) Chandigarh, Sector 12, Chandigarh, 160 012, India.

Department of Pediatrics, Post Graduate Institute for Medical Education and Research (PGIMER) Chandigarh, Chandigarh, India.

出版信息

Egypt Heart J. 2021 May 3;73(1):43. doi: 10.1186/s43044-021-00167-4.

Abstract

BACKGROUND

Pulmonary artery thrombosis is rare in neonates and mimics as persistent pulmonary hypertension or congenital heart disease. Risk factors include septicemia, dehydration, polycythemia, maternal diabetes, asphyxia, and inherited thrombophilias. They present with cyanosis and respiratory distress. Careful echocardiogram assessment helps in identifying the thrombus in the pulmonary artery and its branches. Computed tomography pulmonary angiography confirms the diagnosis.

CASE PRESENTATION

We present a case of term neonate who presented with respiratory distress and cyanosis and a detailed echocardiogram revealed thrombus in the origin of left pulmonary artery. The neonate was managed initially with unfractionated heparin and later with low molecular weight heparin with which there was significant resolution of the thrombus CONCLUSION: Spontaneous pulmonary artery thrombosis though rare should be suspected in any cyanotic neonate with respiratory distress. Management in these cases depends on the haemodynamic instability and lung ischemia.

摘要

背景

新生儿肺动脉血栓形成罕见,易被误诊为持续性肺动脉高压或先天性心脏病。危险因素包括败血症、脱水、红细胞增多症、母亲糖尿病、窒息和遗传性易栓症。患儿表现为紫绀和呼吸窘迫。仔细的超声心动图评估有助于识别肺动脉及其分支内的血栓。计算机断层扫描肺动脉造影可确诊。

病例报告

我们报告一例足月儿,表现为呼吸窘迫和紫绀,详细的超声心动图显示左肺动脉起始处有血栓。该新生儿最初接受普通肝素治疗,后来改用低分子肝素,血栓明显溶解。结论:虽然自发性肺动脉血栓形成罕见,但任何出现呼吸窘迫的紫绀新生儿都应怀疑此病。这些病例的治疗取决于血流动力学不稳定和肺缺血情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aec5/8093342/bc40dac50e0d/43044_2021_167_Fig1_HTML.jpg

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