1Division of Infectious Diseases, Department of Internal Medicine, University of California-Davis Health, Sacramento, California.
2Department of Pathology and Laboratory Medicine, University of California-Davis Health, Sacramento, California.
Am J Trop Med Hyg. 2021 May 3;104(6):2065-2068. doi: 10.4269/ajtmh.20-0632.
Clonorchis sinensis, a trematode prevalent in East Asia, causes hepatobiliary infection. Exposure typically occurs through ingestion of raw or undercooked fish containing the encysted larval form of the parasite. Extrahepatobiliary disease has not commonly been described. In this case report, we describe an unusual case of C. sinensis infection associated with eosinophilic pneumonia. A middle-aged man from China presented with subacute cough and was found to have a bilateral diffuse eosinophilic pneumonia with associated peripheral eosinophilia. Stool microscopy revealed C. sinensis eggs, and the patient improved after treatment with prednisone and praziquantel. Pulmonary clonorchiasis should be considered in patients with eosinophilic pneumonia from areas highly endemic for this pathogen.
华支睾吸虫，一种流行于东亚地区的吸虫，可引起肝胆感染。感染通常通过摄入含有寄生虫囊蚴的生的或未煮熟的鱼类而发生。肝外疾病并不常见。在本病例报告中，我们描述了一例与嗜酸细胞性肺炎相关的华支睾吸虫感染的不常见病例。一名来自中国的中年男性表现为亚急性咳嗽，被发现患有双侧弥漫性嗜酸细胞性肺炎，并伴有外周血嗜酸粒细胞增多。粪便显微镜检查显示华支睾吸虫卵，患者在接受泼尼松和吡喹酮治疗后病情改善。在该病原体高度流行的地区，对于嗜酸细胞性肺炎患者，应考虑肺吸虫病。
