Ashwal Eran, Attali Emmanuel, Melamed Nir, Haratz Karina Krajden, Aviram Amir, Hadar Eran, Yogev Yariv, Hiersch Liran
Department of Obstetrics and Gynecology, Lis Hospital for Women, Sourasky Medical Center, Tel Aviv, Israel; Sackler Faculty of Medicine, Tel Aviv University, Israel.
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada.
Eur J Obstet Gynecol Reprod Biol. 2021 Jun;261:160-165. doi: 10.1016/j.ejogrb.2021.04.028. Epub 2021 Apr 24.
We assessed the association of early term at first birth (ETB) with the risk of preterm birth (PTB) and ETB in women with 3 consecutive deliveries.
We conducted a retrospective cohort study of all women with 3 consecutive singleton births at a single institute from 1994 to 2013. The risk of PTB (<37 weeks), spontaneous PTB and ETB (37-38 weeks) in the 3 delivery was explored.
Of 49,259 women delivered in our center during the study period, 4038 met inclusion criteria. The rate for subsequent PTB, spontaneous PTB and recurrent ETB in the 3 delivery significantly increased as the number of prior ETBs increased. The order of a single prior ETB in one of the first two deliveries was differently associated with the risk of complications in the 3 delivery, which was higher when the prior ETB was more recent to the third delivery.
A history of ETB is associated with the risk of future PTB and recurrent ETB. The risk is related to the number and order of prior ETBs.
我们评估了首次分娩为早期足月产（ETB）与连续三次分娩的女性早产（PTB）风险以及再次发生ETB的相关性。
我们对1994年至2013年在单一机构连续三次单胎分娩的所有女性进行了一项回顾性队列研究。探讨了第三次分娩时早产（<37周）、自发性早产和早期足月产（37 - 38周）的风险。
在研究期间于我们中心分娩的49259名女性中，4038名符合纳入标准。第三次分娩时后续早产、自发性早产和复发性早期足月产的发生率随着既往早期足月产次数的增加而显著上升。前两次分娩中有一次既往早期足月产的顺序与第三次分娩并发症风险的关联不同，当既往早期足月产距离第三次分娩更近时，风险更高。
早期足月产史与未来早产和复发性早期足月产的风险相关。该风险与既往早期足月产的次数和顺序有关。
