Department of High-Risk Pregnancy, Clinic of Gynecology and Obstetrics "Narodni Front", Belgrade, Serbia.
Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
Hypertens Pregnancy. 2021 May;40(2):162-170. doi: 10.1080/10641955.2021.1921790. Epub 2021 May 3.
: The aim of the study was to assess the potential role of oxidative stress and lipid status in the onset of preeclampsia.: 138 high-risk pregnant women were prospectively followed. Assessment of oxidative stress (TAS, TOS, AOPP and SH groups) and lipid status (t-C, LDL-C, HDL-C, TGC, APO-A1, APO-B) was carried out during the pregnancy.: 30 women developed preeclampsia. TGC, atherogenic index of plasma, TAS and SH levels were higher in women who subsequently developed preeclampsia (p<0.05).: Oxidative stress and lipid status disturbance have a potential role in the onset of preeclampsia in high risk pregnancies.
: 研究目的在于评估氧化应激和脂质状态在子痫前期发病中的潜在作用。对 138 名高危孕妇进行前瞻性随访。在妊娠期间评估氧化应激（TAS、TOS、AOPP 和 SH 组）和脂质状态（t-C、LDL-C、HDL-C、TGC、APO-A1、APO-B）。有 30 名妇女发生子痫前期。随后发生子痫前期的妇女 TGC、血浆致动脉粥样硬化指数、TAS 和 SH 水平较高（p<0.05）。氧化应激和脂质状态紊乱在高危妊娠子痫前期的发病中具有潜在作用。
