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法勒厄斯-韦耶伦斯效应:血小板和白细胞在流经分支的血流中靠边。

Fåhraeus-Vejlens effect: margination of platelets and leukocytes in blood flow through branches.

作者信息

Perkkiö J, Wurzinger L J, Schmid-Schönbein H

机构信息

Department of Medical Physics, University of Helsinki, Finland.

出版信息

Thromb Res. 1988 May 1;50(3):357-64. doi: 10.1016/0049-3848(88)90265-4.

DOI:10.1016/0049-3848(88)90265-4
PMID:3394121
Abstract

The distribution of platelets and leukocytes was studied in tube flow at T-junctions. The diameters were 200 microns for the main channel and 100 microns for the side branch, or 100 microns and 80 microns, respectively. The concentrations of platelets and leukocytes in the blood collected from the side branch and in the blood from the reservoir were measured using blood samples with different levels of fibrinogen. The concentration of platelets in the blood from the side branch was found to be about 1.2-1.5 times higher than in the reservoir. This ratio was found dependent on the feed hematocrit and fibrinogen concentration. The concentration of leukocytes in the blood from the side branch was about 0.9-1.4 times the value of the blood in the reservoir depending slightly on the fibrinogen concentration.

摘要

研究了T型连接处管流中血小板和白细胞的分布情况。主通道直径为200微米,侧支直径为100微米,或者分别为100微米和80微米。使用含有不同纤维蛋白原水平的血样,测量了从侧支采集的血液以及储液器中血液里血小板和白细胞的浓度。发现侧支血液中血小板的浓度比储液器中的高约1.2至1.5倍。该比例取决于进料血细胞比容和纤维蛋白原浓度。侧支血液中白细胞的浓度约为储液器中血液浓度的0.9至1.4倍,且略微依赖于纤维蛋白原浓度。

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