• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

T型连接处的血浆和血小板撇取

Plasma and platelet skimming at T-junctions.

作者信息

Perkkiö J, Wurzinger L J, Schmid-Schönbein H

出版信息

Thromb Res. 1987 Mar 1;45(5):517-26. doi: 10.1016/0049-3848(87)90314-8.

DOI:10.1016/0049-3848(87)90314-8
PMID:3590090
Abstract

Separation of plasma, erythrocytes, and platelets was studied in T-shaped bifurcations prepared by a casting technique. The diameters of the side and main channel were 100 microns and 200 microns, respectively. Small blood samples (about 20 microliters) were collected from the side channel for determination of erythrocyte and platelet concentrations which were compared to the corresponding values in the reservoir. Conversely to the well-known erythrocyte reduction due to plasma skimming a relative enrichment of platelets in the side branch was observed. The thickness of the plasma layer in the main channel was found to depend on the aggregation tendency of the erythrocytes for Reynolds numbers around 0.3.

摘要

通过铸造技术制备的T形分叉结构中血浆、红细胞和血小板的分离情况得到了研究。侧通道和主通道的直径分别为100微米和200微米。从侧通道采集少量血液样本(约20微升)以测定红细胞和血小板浓度,并与储液器中的相应值进行比较。与因血浆撇取导致红细胞减少这一众所周知的情况相反,观察到侧支中血小板相对富集。发现主通道中血浆层的厚度取决于红细胞在雷诺数约为0.3时的聚集趋势。

相似文献

1
Plasma and platelet skimming at T-junctions.T型连接处的血浆和血小板撇取
Thromb Res. 1987 Mar 1;45(5):517-26. doi: 10.1016/0049-3848(87)90314-8.
2
Blood viscosity, mass transport, and thrombogenesis.血液粘度、物质运输与血栓形成。
Prog Hemost Thromb. 1982;6:139-77.
3
A numerical study of plasma skimming in small vascular bifurcations.小血管分支中血浆撇取的数值研究。
J Biomech Eng. 1994 Feb;116(1):79-88. doi: 10.1115/1.2895708.
4
Plasma skimming in vascular trees: numerical estimates of symmetry recovery lengths.血管树中的血浆撇除:对称恢复长度的数值估计
Microcirculation. 1995 Dec;2(4):345-53. doi: 10.3109/10739689509148278.
5
The yield shear stress of blood in branched models of the microcirculation. Effect of hematocrit and plasma macromolecules.微循环分支模型中血液的屈服剪应力。血细胞比容和血浆大分子的影响。
Bibl Haematol. 1981(47):14-20. doi: 10.1159/000402206.
6
Fåhraeus-Vejlens effect: margination of platelets and leukocytes in blood flow through branches.法勒厄斯-韦耶伦斯效应:血小板和白细胞在流经分支的血流中靠边。
Thromb Res. 1988 May 1;50(3):357-64. doi: 10.1016/0049-3848(88)90265-4.
7
Microvascular blood flow resistance: Role of red blood cell migration and dispersion.微血管血流阻力:红细胞迁移与扩散的作用。
Microvasc Res. 2015 May;99:57-66. doi: 10.1016/j.mvr.2015.02.006. Epub 2015 Feb 25.
8
A three-dimensional analysis of plasma skimming at microvascular bifurcations.微血管分叉处血浆撇取的三维分析。
Microvasc Res. 1991 Jul;42(1):17-38. doi: 10.1016/0026-2862(91)90072-j.
9
Motion, deformation, and interaction of blood cells and plasma during flow through narrow capillary tubes.血液细胞和血浆在流经狭窄毛细血管时的运动、变形及相互作用。
Blood Cells. 1980;6(4):799-817.
10
Plasma skimming in serial microvascular bifurcations.连续微血管分支中的血浆撇取
Microvasc Res. 1990 Sep;40(2):179-90. doi: 10.1016/0026-2862(90)90017-l.

引用本文的文献

1
Dynamics of blood flow and thrombus formation in a multi-bypass microfluidic ladder network.多旁路微流控梯形网络中的血流动力学和血栓形成
Cell Mol Bioeng. 2017 Feb;10(1):16-29. doi: 10.1007/s12195-016-0470-7. Epub 2016 Oct 20.
2
Spatial distributions of red blood cells significantly alter local haemodynamics.红细胞的空间分布会显著改变局部血流动力学。
PLoS One. 2014 Jun 20;9(6):e100473. doi: 10.1371/journal.pone.0100473. eCollection 2014.
3
The effect of red blood cell aggregation on velocity and cell-depleted layer characteristics of blood in a bifurcating microchannel.
红细胞聚集对分支微通道中血流速度和细胞耗尽层特征的影响。
Biomicrofluidics. 2012 May 11;6(2):24119. doi: 10.1063/1.4717755. Print 2012 Jun.
4
Topology and hemodynamics of the cortical cerebrovascular system.皮质脑血管系统的拓扑结构和血液动力学。
J Cereb Blood Flow Metab. 2012 Jun;32(6):952-67. doi: 10.1038/jcbfm.2012.39. Epub 2012 Apr 4.
5
Model of platelet transport in flowing blood with drift and diffusion terms.具有漂移和扩散项的流动血液中血小板运输模型。
Biophys J. 1991 Jul;60(1):53-69. doi: 10.1016/S0006-3495(91)82030-6.