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动脉导管未闭支架置入术中的肺动脉分支嵌顿:招募和即刻结果。

Branch Pulmonary Artery Jailing During Patent Ductus Arteriosus Stenting: Recruitment and Immediate Outcomes.

机构信息

Pediatric Cardiac Services, 501944Narayana Institute of Cardiac Sciences, Bengaluru, India.

出版信息

World J Pediatr Congenit Heart Surg. 2021 May;12(3):320-330. doi: 10.1177/2150135120980388.

DOI:10.1177/2150135120980388
PMID:33942686
Abstract

BACKGROUND

Branch pulmonary artery (PA) occlusion during patent ductus arteriosus (PDA) stenting procedure is the main reason why branch PA origin stenosis was considered as a contraindication for PDA stenting. This study was designed to assess the incidence of branch PA jailing during PDA stenting for cyanotics with duct-dependent pulmonary circulation and its immediate outcome.

METHODS

All the completed PDA stenting patients in our hospital between April 2017 and June 2019 were retrospectively analyzed for branch PA jailing and its outcome.

RESULTS

Of 63 completed PDA stenting, there was branch PA jailing in 13 (20.6%) patients, all successfully recruited either by strut dilatation or by surgery. The median duration of ventilation was 16 (interquartile range [IQR]: 8-22) hours for jailed patients and 17.5 (IQR: 5.25-34.25) hours for nonjailed patients ( = .978). Median intensive care unit [ICU] stay was 69 (IQR: 47.75-96) hours for jailed patients and 79.5 (IQR: 66.75-135.25) hours for nonjailed patients ( = .394). Procedural mortality was 1 (7.6%) for jailed patients and 3 (6%) for nonjailed patients. Since all the jailed pulmonary arteries were recruited, there was proportionate growth of branch PA till the most recent follow-up.

CONCLUSION

Jailing of branch PA does not increase the ventilation duration, ICU stay, or mortality risk if recruited immediately. Proportionate growth of branch PAs can be achieved in spite of jailing, if addressed aggressively. Branch PA stenosis should not be considered as a contraindication for PDA stenting.

摘要

背景

动脉导管未闭(PDA)支架置入术中分支肺动脉(PA)闭塞是导致分支 PA 起源狭窄被认为是 PDA 支架置入术禁忌的主要原因。本研究旨在评估青紫型依赖导管循环的 PDA 患者在 PDA 支架置入术中分支 PA 嵌顿的发生率及其即刻结果。

方法

回顾性分析我院 2017 年 4 月至 2019 年 6 月期间所有完成的 PDA 支架置入术患者的分支 PA 嵌顿及其结果。

结果

63 例完成的 PDA 支架置入术中,有 13 例(20.6%)患者发生分支 PA 嵌顿,均通过支架扩张或手术成功复位。嵌顿组患者的通气时间中位数为 16(IQR:8-22)小时,非嵌顿组为 17.5(IQR:5.25-34.25)小时( =.978)。嵌顿组患者的 ICU 住院时间中位数为 69(IQR:47.75-96)小时,非嵌顿组为 79.5(IQR:66.75-135.25)小时( =.394)。嵌顿组患者的手术死亡率为 1 例(7.6%),非嵌顿组为 3 例(6%)。由于所有嵌顿的肺动脉均被成功复位,因此在最近的随访中,分支 PA 均按比例生长。

结论

如果立即进行嵌顿复位,分支 PA 嵌顿不会增加通气时间、ICU 住院时间或死亡率风险。如果积极处理,尽管存在嵌顿,但仍可实现分支 PA 的按比例生长。因此,分支 PA 狭窄不应被视为 PDA 支架置入术的禁忌证。

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引用本文的文献

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Pediatr Cardiol. 2025 May 2. doi: 10.1007/s00246-025-03874-w.
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Pre-Catheterization Computed Tomography Angiography Aids in the Selection of Ductus Arteriosus Stent Length for Ductal-Dependent Pulmonary Blood Flow.心导管插入术前计算机断层血管造影有助于选择用于依赖动脉导管的肺血流的动脉导管支架长度。
Pediatr Cardiol. 2025 Jan 6. doi: 10.1007/s00246-024-03731-2.
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Stenting of the Patent Ductus Arteriosus: A Meta-analysis and Literature Review.
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J Soc Cardiovasc Angiogr Interv. 2022 Jul 7;1(6):100392. doi: 10.1016/j.jscai.2022.100392. eCollection 2022 Nov-Dec.
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Erratum: Stenting of the Patent Ductus Arteriosus: A Meta-analysis and Literature Review.勘误:动脉导管未闭的支架置入术:一项荟萃分析与文献综述。
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