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心导管插入术前计算机断层血管造影有助于选择用于依赖动脉导管的肺血流的动脉导管支架长度。

Pre-Catheterization Computed Tomography Angiography Aids in the Selection of Ductus Arteriosus Stent Length for Ductal-Dependent Pulmonary Blood Flow.

作者信息

Williams Wadsworth A, Cornicelli Matthew, Husain Nazia, Fox Jeremy, Nugent Alan W, Tannous Paul, O'Halloran Conor P

机构信息

Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA.

Division of Cardiology, Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago and Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

出版信息

Pediatr Cardiol. 2025 Jan 6. doi: 10.1007/s00246-024-03731-2.

Abstract

PDA stenting is increasingly utilized for patients with ductal-dependent pulmonary blood flow. Predicting optimal stent length prior to and during the intervention remains a challenge. The utility of pre-catheterization computed tomography angiography (CTA) to predict stent length was evaluated. All patients that received a PDA stent for pulmonary blood flow between 2019 and 2022 with a pre-stent CTA were reviewed. Several CTA and catheter angiography-based measurements of the native and stented PDA were performed. Curvilinear and straight-line PDA lengths were determined by pre-catheterization CTA and used to calculate the tortuosity index ([Curvilinear-Straight]/Curvilinear). The stented ductal length (SDL) was determined by catheter angiography after stent deployment by subtracting the aortic and pulmonary overhang from the total stent length. A linear regression model was created using an Akaike information criteria (AIC) analysis to identify CTA measurements that correlate with SDL. 31 patients met inclusion criteria. The SDL lies between the pre-stent CTA straight length (mean of 11.6 mm) and curvilinear length (mean of 17.8 mm) for most patients. As the PDA tortuosity index increases, the curvilinear length increases exponentially, while the SDL remains closer to the straight length. From our AIC analysis, only CTA straight length was significantly associated with SDL. Linear regression modeling predicts that the SDL is 1.14 times the CTA straight length (R = 0.97, p < 0.001). Pre-intervention CTA can aid in the selection of PDA stent length prior to catheterization. The SDL is well approximated by the pre-stent CTA straight length with a small correction.

摘要

动脉导管未闭(PDA)支架置入术越来越多地应用于依赖导管的肺血流患者。在介入治疗前和治疗过程中预测最佳支架长度仍然是一项挑战。我们评估了导管插入术前计算机断层扫描血管造影(CTA)预测支架长度的效用。回顾了2019年至2022年间所有接受PDA支架治疗肺血流且术前有CTA的患者。对未置入支架和置入支架后的PDA进行了基于CTA和导管血管造影的多项测量。通过导管插入术前CTA确定曲线和直线的PDA长度,并用于计算迂曲指数([曲线长度-直线长度]/曲线长度)。支架置入后,通过导管血管造影,从总支架长度中减去主动脉和肺动脉突出部分,确定支架置入后的导管长度(SDL)。使用赤池信息准则(AIC)分析创建线性回归模型,以识别与SDL相关的CTA测量值。31名患者符合纳入标准。大多数患者的SDL介于术前CTA直线长度(平均11.6mm)和曲线长度(平均17.8mm)之间。随着PDA迂曲指数增加,曲线长度呈指数增加,而SDL更接近直线长度。根据我们的AIC分析,只有CTA直线长度与SDL显著相关。线性回归模型预测SDL是CTA直线长度的1.14倍(R = 0.97,p < 0.001)。介入治疗前的CTA有助于在导管插入术前选择PDA支架长度。通过对术前CTA直线长度进行小的校正,可以很好地估算SDL。

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