Posgrado en Ciencias Biológicas, Facultad de Biología, Universidad Autónoma de Sinaloa, Culiacán, México.
Posgrado en Ciencias Biomédicas, Facultad de Ciencias Químico Biológicas, Universidad Autónoma de Sinaloa, Culiacán, México.
Vector Borne Zoonotic Dis. 2021 Jun;21(6):478-481. doi: 10.1089/vbz.2020.2748. Epub 2021 May 3.
Dengue virus (DENV) is transmitted to humans by the bite of the vector . Several researchers have suggested that the mechanism of vertical transmission of DENV in the vector is a key aspect for the prevalence of the virus in the environment and the potentiation of epidemic outbreaks of the disease. In this context and as part of an integrated study of DENV serotypes in mosquitoes of urban areas in Sinaloa, Mexico, the presence of DENV-4 in larval stages of was evaluated to demonstrate the vertical transmission of this serotype. In total, 672 larvae of were collected in 16 sectors and were grouped into 36 pools, of which 41.66% (15/36 pools) tested positive for DENV-4, with a minimum infection rate = 22.32. The analysis of the obtained sequences showed a 98% similarity to the DENV-4 with sequences previously reported in GenBank. These results show that acts as a natural reservoir for DENV-4 in this region.
登革病毒（DENV）通过蚊子的叮咬传播给人类。一些研究人员认为，DENV 在蚊子中的垂直传播机制是病毒在环境中流行和疾病爆发潜力增强的关键方面。在这方面，作为墨西哥锡那罗亚州城区蚊子中 DENV 血清型综合研究的一部分，评估了幼虫阶段的 DENV-4 的存在，以证明该血清型的垂直传播。总共从 16 个区收集了 672 只 的幼虫，并将其分为 36 个池，其中 41.66%（15/36 个池）检测到 DENV-4 阳性，最低感染率 = 22.32。对获得的序列分析表明，与 GenBank 中先前报道的 DENV-4 序列具有 98%的相似性。这些结果表明，在该地区， 是 DENV-4 的天然宿主。
