Department of Neurosurgery, Stanford University, Stanford, CA, USA.
Dev Cell. 2021 May 3;56(9):1215-1217. doi: 10.1016/j.devcel.2021.04.015.
In the myelin field, there is a lack of reliable in vitro tools to study myelination, especially using human cells. In this issue of Developmental Cell, James et al. present a guide to generating human iPSC-derived "myelinoids"-3D models of myelination that reliably achieve mature myelin formation.
在髓鞘领域，缺乏可靠的体外工具来研究髓鞘形成，特别是使用人类细胞。在本期《发育细胞》中，James 等人介绍了一种生成人诱导多能干细胞衍生的“髓鞘样细胞”的指南，这是一种可靠的髓鞘形成 3D 模型。
