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能否通过儿童血常规参数确定复发性鼻出血?

Can we determine recurrent epistaxis by hemogram parameters in children?

机构信息

Adana Çukurova State Hospital, Otorhinolaryngology Department, Adana, Turkey.

Nizip State Hospital, Otorhinolaryngology Department, Gaziantep, Turkey.

出版信息

Int J Pediatr Otorhinolaryngol. 2021 Jul;146:110747. doi: 10.1016/j.ijporl.2021.110747. Epub 2021 Apr 27.

Abstract

OBJECTIVE

Epistaxis in children is a common reason for admission at otolaryngology outpatient clinics. Patients are diagnosed by clinical examination and laboratory tests. We aimed to evaluate epistaxis using simple blood parameters useful for diagnosis.

MATERIAL AND METHODS

This study includes a retrospective analysis of 240 patients, including 120 study group and 120 healthy pediatric patients, who applied to the ENT outpatient clinic with the diagnosis of epistaxis between 2018 and 2020. This study is designed to analyze the predictive values of neutrophil-lymphocyte ratio (NLR), eosinophil-LR (ELR), platelet-LR (PLR), plateletcrit (PCT), mean platelet volume (MPV), and platelet distribution width (PDW) in pediatric epistaxis.

RESULTS

Serological factors were assessed and no statistical associations in MPV, PDW, PLR, and ELR values were found. However, significant changes were found for PCT and NLR within the patient and control groups. The average PCT was lower in the study group in comparison to the controls (p = 0.022). The average NLR was higher in the study group in comparison to the controls (p = 0.004).

CONCLUSION

The examination of children with epistaxis, as well as their management, following admission to the outpatient clinic continues to evolve. Although many studies have investigated the hemogram parameters and platelet indices, the PCT value has never been investigated in epistaxis. To our knowledge, our study is the first to demonstrate a relationship to PCT values and epistaxis.

摘要

目的

儿童鼻出血是耳鼻喉科门诊就诊的常见原因。通过临床检查和实验室检查进行诊断。我们旨在使用对诊断有用的简单血液参数评估鼻出血。

材料与方法

本研究包括对 240 名患者的回顾性分析,包括 2018 年至 2020 年间因鼻出血就诊于耳鼻喉科门诊的 120 名研究组和 120 名健康儿科患者。本研究旨在分析中性粒细胞与淋巴细胞比值(NLR)、嗜酸性粒细胞与淋巴细胞比值(ELR)、血小板与淋巴细胞比值(PLR)、血小板比容(PCT)、平均血小板体积(MPV)和血小板分布宽度(PDW)在儿科鼻出血中的预测价值。

结果

评估了血清学因素,并且在 MPV、PDW、PLR 和 ELR 值方面未发现统计学关联。然而,在患者和对照组中,PCT 和 NLR 有显著变化。与对照组相比,研究组的平均 PCT 较低(p=0.022)。与对照组相比,研究组的平均 NLR 较高(p=0.004)。

结论

对住院后就诊的儿童鼻出血的检查及其管理仍在不断发展。尽管许多研究已经研究了血液参数和血小板指数,但 PCT 值从未在鼻出血中进行过研究。据我们所知,我们的研究首次证明了 PCT 值与鼻出血之间的关系。

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