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血小板指数在确定 COVID-19 患者是否应作为门诊或住院患者进行治疗中的作用:一项回顾性研究。

Platelet Indices' Usefulness in Determining whether Patients with COVID-19 Should be Treated as an Outpatient or Inpatient: a Retrospective Study.

出版信息

Clin Lab. 2021 Jul 1;67(7). doi: 10.7754/Clin.Lab.2020.201144.

DOI:10.7754/Clin.Lab.2020.201144
PMID:34258979
Abstract

BACKGROUND

Coronavirus disease 2019 (COVID-19) has affected the health system around the world. It is necessary to facilitate health care services with useful parameters in patient follow-up. In this study, we wanted to determine whether platelet indices can be used as an assistant parameter in the clinician's decision-making process regarding which of the patients diagnosed with COVID-19 should be treated by hospitalization.

METHODS

This retrospective study was performed in a secondary care hospital in Mugla, Turkey. Demographic information such as age, gender, and comorbidities of patients admitted to the emergency pandemic outpatient clinic within five months and diagnosed with COVID-19, as well as discharge, hospitalization, or intensive care needs (ICU), and thirty-day mortality were noted. Also, patients with platelet count (PLT), mean platelet volume (MPV), platelet distribution width (PDW), thrombocytocrit (PCT), MPV/PLT, MPV/PCT, PDW/PLT, PDW/PCT values for outpatient follow-up, hospitalization, intensive care unit need, and 30-day mortality relationships were examined.

RESULTS

A total of 93 patients diagnosed with COVID-19 were included in the study. It was observed that those with comorbidity had a statistically significant higher rate of hospitalization (p = 0.013). No statistically significant difference was found between outpatients and inpatients in terms of PLT, MPV, PDW, PCT, MPV/PLT, MPV/ PCT, PDW/PLT, and PDW/PCT (p > 0.05 for each).

CONCLUSIONS

Platelet indices such as PLT, MPV, PDW, PCT, MPV/PLT, MPV/PCT, PDW/PLT, and PDW/PCT are not useful parameters for the clinician to distinguish between outpatient and inpatient treatment of patients with COVID-19.

摘要

背景

2019 年冠状病毒病(COVID-19)已对全球卫生系统造成影响。在患者随访中,需要利用有用的参数来促进医疗保健服务。在这项研究中,我们想确定血小板指数是否可作为临床医生决策过程中的辅助参数,以确定应将哪些确诊 COVID-19 的患者住院治疗。

方法

这是在土耳其穆拉的一家二级保健医院进行的回顾性研究。记录了在五个月内进入急诊大流行门诊并被诊断为 COVID-19 的患者的人口统计学信息,如年龄、性别和合并症,以及出院、住院或需要重症监护(ICU)以及 30 天死亡率。还检查了门诊随访、住院、重症监护病房需要以及 30 天死亡率的患者的血小板计数(PLT)、平均血小板体积(MPV)、血小板分布宽度(PDW)、血小板压积(PCT)、MPV/PLT、MPV/PCT、PDW/PLT、PDW/PCT 值之间的关系。

结果

共纳入 93 例确诊 COVID-19 的患者。患有合并症的患者住院率显著更高(p=0.013)。门诊和住院患者在 PLT、MPV、PDW、PCT、MPV/PLT、MPV/PCT、PDW/PLT 和 PDW/PCT 方面无统计学显著差异(p>0.05)。

结论

PLT、MPV、PDW、PCT、MPV/PLT、MPV/PCT、PDW/PLT 和 PDW/PCT 等血小板指数对于临床医生区分 COVID-19 患者的门诊和住院治疗并无帮助。

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