Follick M J, Gorkin L, Capone R J, Smith T W, Ahern D K, Stablein D, Niaura R, Visco J
Brown University/Miriam Hospital, Providence, RI 02906.
Am Heart J. 1988 Jul;116(1 Pt 1):32-6. doi: 10.1016/0002-8703(88)90246-3.
A prospective study examining the relationship between psychological distress and ventricular ectopy was conducted with 125 post-myocardial infarction patients equipped with a transtelephonic ECG monitor. Subjects were subsequently grouped according to the occurrence (n = 59) or nonoccurrence (n = 65) of ventricular arrhythmias over a 1-year period. Results indicated a direct relationship between self-reported distress levels and occurrence of ectopic beats. This relationship was unaltered by adjusting simultaneously for known predictors of arrhythmias, including cardiac risk, age, and the prescription of beta-blocker agents. Thus this study represents an initial demonstration in a post-myocardial infarction population that psychosocial factors have prognostic significance for arrhythmias and, presumably, sudden death.
一项前瞻性研究对125名配备了遥测心电图监测仪的心肌梗死后患者进行了心理困扰与室性早搏关系的研究。随后，根据患者在1年期间是否发生室性心律失常（发生组n = 59，未发生组n = 65）进行分组。结果表明，自我报告的困扰程度与异位搏动的发生之间存在直接关系。通过同时调整心律失常的已知预测因素，包括心脏风险、年龄和β受体阻滞剂的处方，这种关系并未改变。因此，本研究首次证明，在心肌梗死后人群中，社会心理因素对心律失常以及可能的猝死具有预后意义。
