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窦管区稳定技术改良主动脉置换术的早期安全性效果。

Early safety performance of a modified technique of aorta replacement with sinotubular stabilization.

机构信息

GVM Care & Research, Anthea Hospital, Bari, Italy.

GVM Care & Research, Maria Eleonora Hospital, Palermo, Italy.

出版信息

Asian Cardiovasc Thorac Ann. 2022 Feb;30(2):171-176. doi: 10.1177/02184923211015094. Epub 2021 May 4.

DOI:10.1177/02184923211015094
PMID:33947228
Abstract

BACKGROUND

We sought to determine if a modified technique for ascending aorta replacement with sinotubular junction reduction and stabilization was safe.

METHODS

This technique was performed by suspension of the three commissures, invagination of the aortic Dacron graft and advancing the graft into the ventricles. We included patients with dilatation of the ascending aorta, normal sinuses of Valsalva dimension (<45 mm), with or without aortic annulus enlargement (>25 mm) and with various degree of aortic insufficiency (from grade 1 to 3).

RESULTS

From April to October 2019, 20 patients were recruited from two centers; mean age was 66.9 ± 12.8 years, 13 were male; grade 1, 2 and 3 was present in 12, 2 and 6 patients, respectively. All patients underwent ascending aorta replacement with modified technique; an additional open subvalvular ring was used in 8 patients with aortic insufficiency ≥ 2; cusps repair was performed in 6 patients (5 plicating central stitches/1 shaving); concomitant coronary artery bypass grafting was performed in 10 patients. There was no 30-day mortality. One patient was re-explored for bleeding. All patients completed six-month follow-up; at the transthoracic echocardiography, there was no aortic insufficiency ≥ 1 except one patient with aortic insufficiency grade 1 who underwent ascending aorta replacement and subvalvular ring; no patients underwent reintervention.

CONCLUSIONS

This modified technique for ascending aorta replacement and sinotubular junction stabilization was safe. It could be associated with other aortic valve sparing techniques. However, such remodeling approach has to be validated in a larger cohort of patients with longer follow-up.

摘要

背景

我们旨在确定一种改良的升主动脉置换技术,包括窦管交界部缩小和稳定,是否安全。

方法

该技术通过悬吊三个交界、主动脉涤纶移植物内翻并将移植物推进心室来完成。我们纳入了升主动脉扩张、窦管交界正常(<45mm)、伴或不伴主动脉瓣环扩大(>25mm)和不同程度主动脉瓣关闭不全(1 至 3 级)的患者。

结果

2019 年 4 月至 10 月,我们从两个中心招募了 20 名患者;平均年龄为 66.9±12.8 岁,13 名男性;12 名患者存在 1 级、2 级和 3 级主动脉瓣关闭不全,分别为 2 名和 6 名;所有患者均接受改良技术升主动脉置换术;8 名主动脉瓣关闭不全≥2 级的患者采用开放式瓣下环;6 名患者行瓣叶修复(5 例中央缝线折叠/1 例瓣叶削薄);10 名患者同期行冠状动脉旁路移植术。无 30 天死亡率。1 例患者因出血再次探查。所有患者完成 6 个月随访;经胸超声心动图检查,除 1 例升主动脉置换和瓣下环患者存在 1 级主动脉瓣关闭不全外,无其他患者存在≥1 级主动脉瓣关闭不全;无患者再次介入治疗。

结论

这种改良的升主动脉置换和窦管交界稳定技术是安全的。它可以与其他保留主动脉瓣技术联合应用。然而,这种重塑方法需要在更大的患者队列中进行验证,并进行更长时间的随访。

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