Ma Shuang, Kan Baotian, Jian Xiangdong, Li Chenglin, Zheng Yingying, Sun Cece, Tao Yiming, Cui Siqi, Jian Tianzi
School of Nursing, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Department of Poisoning and Occupational Diseases, Emergency, Qilu Hospital, Shandong University, Jinan, Shandong, China.
J Int Med Res. 2021 May;49(5):3000605211010734. doi: 10.1177/03000605211010734.
Secondary organizing pneumonia (SOP) is a nonspecific inflammatory response towards acute lung injuries caused by various diseases. However, organizing pneumonia (OP) secondary to occupational acute nitrogen oxide poisoning has been reported rarely. We report a 49-year-old man who suffered from nitrogen oxide poisoning after inhaling mixed gas at work. After pathological examination, he was diagnosed with OP. In the absence of other underlying factors causing OP, he was diagnosed with SOP owing to acute nitrogen oxide poisoning. After systematic treatment, the patient recovered and was discharged in better health. In patients with lung injury caused by acute nitrogen oxide poisoning, physicians should be alert to the risk of patients subsequently developing SOP, and timely diagnosis and treatment are essential for complete recovery.
继发性机化性肺炎（SOP）是对各种疾病引起的急性肺损伤的一种非特异性炎症反应。然而，职业性急性氮氧化物中毒继发的机化性肺炎（OP）报道较少。我们报告一例49岁男性，其在工作中吸入混合气体后发生氮氧化物中毒。经病理检查，诊断为OP。在无其他导致OP的潜在因素的情况下，因其急性氮氧化物中毒而诊断为SOP。经系统治疗后，患者康复，健康状况较好出院。对于急性氮氧化物中毒所致肺损伤的患者，医生应警惕患者随后发生SOP的风险，及时诊断和治疗对于完全康复至关重要。
