Vietnam National Heart Institute, Bach Mai Hospital, 78 Giai Phong Road, Dong Da District, Hanoi, 100000, Vietnam.
Department of Cardiology, Hanoi Medical University, 1 Ton That Tung Street, Dong Da District, Hanoi, 100000, Vietnam.
BMC Cardiovasc Disord. 2021 May 5;21(1):229. doi: 10.1186/s12872-021-02026-1.
Little is known about the quality of life (QOL) and health status of adults with congenital heart disease (CHD) in developing countries. Therefore, this study aimed to describe the QOL and health status of hospitalized adults with CHD in Vietnam and investigate the association between QOL and their biological-social characteristics.
A cross-sectional study was conducted with 109 adults with CHD, hospitalized in the Vietnam National Heart Institute, between June and December 2019. Validated instruments to assess QOL and health status describing patient-reported outcomes were used, including the EuroQOL-5 Dimensions-5 Level, Satisfaction with Life Scale, and Hospital Anxiety and Depression Scale.
The mean scores on the EuroQOL-descriptive system (EQ-DS) and EuroQOL visual analogue scale (EQ-VAS) were 0.792 (SD = 0.122, 95% confidence interval [CI] 0.769-0.815) and 66.3 (SD = 12.5, 95% CI 63.9-68.7), respectively. A total of 9.2% (n = 9) patients experienced life dissatisfaction. The prevalence of anxiety and depression were 18.7% (n = 20) and 11% (n = 12), respectively. Scores of QOL in patients aged > 30 years were lower than in those aged ≤ 30 years. Stratified multivariate logistic regression revealed that poor QOL related to being unemployed/unstable employment (OR 4.43, 95% CI 1.71-11.47, p = 0.002), life dissatisfaction associated with unmarried status (OR 4.63, 95% CI 1.2-17.86, p = 0.026), anxiety regarding unemployment/unstable employment (OR 3.88, 95% CI 1.27-11.84, p = 0.017) and complex CHD/PAH (OR 4.84, 95% CI 1.33-17.54, p = 0.016), and depression regarding unemployment/unstable employment (OR 4.63, 95% CI 1.22-17.59, p = 0.003).
Reduced QOL and elevated psychological problems were common experiences among hospitalized adults with CHD in Vietnam. Biological-social characteristics such as unmarried status, unemployment/unstable employment, and complex CHD/PAH related to poor QOL, life dissatisfaction, anxiety, and depression.
关于发展中国家成人先天性心脏病（CHD）患者的生活质量（QOL）和健康状况知之甚少。因此，本研究旨在描述越南住院成人 CHD 患者的 QOL 和健康状况，并调查 QOL 与他们的生物-社会特征之间的关系。
本研究采用横断面研究方法，对 2019 年 6 月至 12 月期间在越南国家心脏研究所住院的 109 名 CHD 成人患者进行研究。使用经过验证的评估 QOL 和健康状况的患者报告结局的工具，包括 EuroQOL-5 维度-5 级量表、生活满意度量表和医院焦虑抑郁量表。
EuroQOL 描述性系统（EQ-DS）和 EuroQOL 视觉模拟量表（EQ-VAS）的平均得分为 0.792（SD=0.122，95%置信区间[CI]0.769-0.815）和 66.3（SD=12.5，95%CI 63.9-68.7）。共有 9.2%（n=9）的患者生活不满。焦虑和抑郁的患病率分别为 18.7%（n=20）和 11%（n=12）。年龄>30 岁的患者的 QOL 评分低于年龄≤30 岁的患者。分层多变量逻辑回归显示，较差的 QOL 与失业/不稳定就业有关（OR 4.43，95%CI 1.71-11.47，p=0.002），生活不满与未婚状态有关（OR 4.63，95%CI 1.2-17.86，p=0.026），焦虑与失业/不稳定就业有关（OR 3.88，95%CI 1.27-11.84，p=0.017）和复杂 CHD/PAH（OR 4.84，95%CI 1.33-17.54，p=0.016），抑郁与失业/不稳定就业有关（OR 4.63，95%CI 1.22-17.59，p=0.003）。
越南住院成人 CHD 患者普遍存在 QOL 降低和心理问题增加的情况。与较差的 QOL、生活不满、焦虑和抑郁相关的生物-社会特征，如未婚状态、失业/不稳定就业和复杂 CHD/PAH。
