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葡萄膜炎与糖尿病

Uveitis and diabetes mellitus.

作者信息

Rothova A, Meenken C, Michels R P, Kijlstra A

机构信息

Department of Ophthalmology, Academic Medical Centre, Amsterdam, The Netherlands.

出版信息

Am J Ophthalmol. 1988 Jul 15;106(1):17-20. doi: 10.1016/s0002-9394(14)76381-0.

DOI:10.1016/s0002-9394(14)76381-0
PMID:3394764
Abstract

Of 340 patients with anterior uveitis, 20 (6%) had diabetes mellitus. This is significantly higher than the prevalence of 1.4% in the normal Dutch population (P less than .001). Of 128 patients with idiopathic anterior uveitis, 16 (12.5%) had diabetes mellitus compared to only four (1.9%) of 212 patients with anterior uveitis with an established specific ocular diagnosis (P less than .001). Of the 16 diabetic patients with idiopathic anterior uveitis, ten (63%) had type I diabetes mellitus and 12 (75%) suffered from severe diabetic complications as angiopathy, nephropathy, and neuropathy. The onset of diabetes mellitus preceded the onset of anterior uveitis in all cases. Whether or not uveitis in diabetic patients is a true inflammation rather than an ischemic phenomenon is still unknown.

摘要

在340例前葡萄膜炎患者中,20例(6%)患有糖尿病。这显著高于荷兰正常人群1.4%的患病率(P<0.001)。在128例特发性前葡萄膜炎患者中,16例(12.5%)患有糖尿病,相比之下,在212例已确诊特定眼部疾病的前葡萄膜炎患者中只有4例(1.9%)患有糖尿病(P<0.001)。在16例患有特发性前葡萄膜炎的糖尿病患者中,10例(63%)患有I型糖尿病,12例(75%)患有严重的糖尿病并发症,如血管病变、肾病和神经病变。在所有病例中,糖尿病的发病均先于前葡萄膜炎。糖尿病患者的葡萄膜炎究竟是真正的炎症还是缺血现象仍不清楚。

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