Gobarani Rukshar K, Zwar Nicholas A, Russell Grant, Abramson Michael J, Bonevski Billie, Holland Anne E, Paul Eldho, Cox Narelle S, Wilson Sally, George Johnson
Centre for Medicine Use and Safety, Faculty of Pharmacy and Pharmaceutical Sciences.
Faculty of Health Sciences and Medicine, Bond University, Queensland, and School of Population Health, University of New South Wales, Sydney.
Br J Gen Pract. 2021 May 27;71(707):e458-e464. doi: 10.3399/BJGP.2020.0906. Print 2021 Jun.
GPs have limited capacity to routinely provide smoking cessation support. New strategies are needed to reach all smokers within this setting.
To evaluate the effect of a pharmacist-coordinated interdisciplinary smoking cessation intervention delivered in Australian general practice.
Secondary analysis of a cluster randomised controlled trial (RCT) conducted in 41 Australian general practices.
In all, 690 current smokers were included in this study: 373 from intervention clinics ( = 21) and 317 from control clinics ( = 18). A total of 166 current smokers had spirometry-confirmed chronic obstructive pulmonary disease (COPD). In the intervention clinics, trained pharmacists provided smoking cessation support plus Quitline referral. Control clinics provided usual care plus Quitline referral. Those with COPD in the intervention group ( = 84) were referred for home medicines review (HMR) and home-based pulmonary rehabilitation (HomeBase), which included further smoking cessation support. Outcomes included carbon monoxide (CO)-validated smoking abstinence, self-reported use of smoking cessation aids, and differences between groups in readiness-to-quit score at 6 months.
Intention-to-treat analysis showed similar CO-validated abstinence rates at 6 months in the intervention (4.0%) and control clinics (3.5%). No differences were observed in readiness-to-quit scores between groups at 6 months. CO-validated abstinence rates were similar in those who completed HMR and at least six sessions of HomeBase to those with COPD in usual care.
A pharmacist-coordinated interdisciplinary smoking cessation intervention when integrated in a general practice setting had no advantages over usual care. Further research is needed to evaluate the effect of HMR and home-based pulmonary rehabilitation on smoking abstinence in smokers with COPD.
全科医生常规提供戒烟支持的能力有限。需要新的策略来帮助该环境下的所有吸烟者戒烟。
评估在澳大利亚全科医疗中开展的由药剂师协调的跨学科戒烟干预措施的效果。
对在41家澳大利亚全科诊所进行的一项整群随机对照试验(RCT)进行二次分析。
本研究共纳入690名当前吸烟者:来自干预诊所的有373名(n = 21),来自对照诊所的有317名(n = 18)。共有166名当前吸烟者经肺功能测定确诊患有慢性阻塞性肺疾病(COPD)。在干预诊所,经过培训的药剂师提供戒烟支持并转介至戒烟热线。对照诊所提供常规护理并转介至戒烟热线。干预组中患有COPD的患者(n = 84)被转介接受家庭药物审查(HMR)和居家肺康复(HomeBase),其中包括进一步的戒烟支持。结局指标包括经一氧化碳(CO)验证的戒烟情况、自我报告的戒烟辅助工具使用情况,以及6个月时两组在戒烟意愿得分上的差异。
意向性分析显示,干预诊所(4.0%)和对照诊所在6个月时经CO验证的戒烟率相似(3.5%)。两组在6个月时的戒烟意愿得分无差异。完成HMR和至少六次HomeBase疗程的患者与接受常规护理的COPD患者经CO验证的戒烟率相似。
在全科医疗环境中实施的由药剂师协调的跨学科戒烟干预措施与常规护理相比并无优势。需要进一步研究来评估HMR和居家肺康复对COPD吸烟者戒烟的影响。