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按种族/族裔划分的确诊糖尿病成年人全因死亡率的趋势和社会经济差异:基于人群的队列研究-美国,1997-2015 年。

Trends and socioeconomic disparities in all-cause mortality among adults with diagnosed diabetes by race/ethnicity: a population-based cohort study - USA, 1997-2015.

机构信息

Division of Diabetes Translation, Centers for Disease Control and Prevention, Atlanta, Georgia, USA

Division of Diabetes Translation, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

出版信息

BMJ Open. 2021 May 4;11(5):e044158. doi: 10.1136/bmjopen-2020-044158.

Abstract

OBJECTIVES

By race/ethnicity and socioeconomic position (SEP), to estimate and examine changes over time in (1) mortality rate, (2) mortality disparities and (3) excess mortality risk attributed to diagnosed diabetes (DM).

DESIGN

Population-based cohort study using National Health Interview Survey data linked to mortality status from the National Death Index from survey year up to 31 December 2015 with 5 years person-time.

PARTICIPANTS

US adults aged ≥25 years with (31 586) and without (332 451) DM.

PRIMARY OUTCOME

Age-adjusted all-cause mortality rate for US adults with DM in each subgroup of SEP (education attainment and income-to-poverty ratio (IPR)) and time (1997-2001, 2002-2006 and 2007-2011).

RESULTS

Among adults with DM, mortality rates fell from 23.5/1000 person-years (p-y) in 1997-2001 to 18.1/1000 p-y in 2007-2011 with changes of -5.2/1000 p-y for non-Hispanic whites; -5.2/1000 p-y for non-Hispanic blacks; and -5.4/1000 p-y for Hispanics. Rates significantly declined within SEP groups, measured as education attainment (<high school=-5.7/1000 p-y; high school graduate=-4.2/1000 p-y; and >high school=-4.8/1000 p-y) and IPR group (poor=-7.9/1000 p-y; middle income=-4.7/1000 p-y; and high income=-6.2/1000 p-y; but not for near poor). For adults with DM, statistically significant all-cause mortality disparity showed greater mortality rates for the lowest than the highest SEP level (education attainment and IPR) in each time period. However, patterns in mortality trends and disparity varied by race/ethnicity. The excess mortality risk attributed to DM significantly decreased from 1997-2001 to 2007-2011, within SEP levels, and among Hispanics and non-Hispanic whites; but no statistically significant changes among non-Hispanic blacks.

CONCLUSIONS

There were substantial improvements in all-cause mortality among US adults. However, we observed SEP disparities in mortality across race/ethnic groups or for adults with and without DM despite targeted efforts to improve access and quality of care among disproportionately affected populations.

摘要

目的

按种族/族裔和社会经济地位(SEP),估计并考察(1)死亡率、(2)死亡率差距和(3)归因于诊断糖尿病(DM)的超额死亡风险随时间的变化。

设计

使用全国健康访谈调查数据进行基于人群的队列研究,该数据与国家死亡指数的死亡状态相联系,调查年份截至 2015 年 12 月 31 日,随访时间为 5 年。

参与者

美国≥25 岁的成年人,其中(31586 人)患有 DM,(332451 人)未患有 DM。

主要结局

DM 患者按 SEP(教育程度和收入与贫困率之比(IPR))和时间(1997-2001、2002-2006 和 2007-2011)在每个 SEP 亚组中的年龄调整全因死亡率。

结果

在患有 DM 的成年人中,死亡率从 1997-2001 年的 23.5/1000 人年(p-y)降至 2007-2011 年的 18.1/1000 p-y,非西班牙裔白人下降了-5.2/1000 p-y;非西班牙裔黑人下降了-5.2/1000 p-y;西班牙裔下降了-5.4/1000 p-y。各 SEP 组的死亡率均显著下降,以教育程度衡量(未完成高中学业=-5.7/1000 p-y;高中学历=-4.2/1000 p-y;高中学历以上=-4.8/1000 p-y)和 IPR 组(贫困=-7.9/1000 p-y;中等收入=-4.7/1000 p-y;高收入=-6.2/1000 p-y;但接近贫困人口组没有)。对于患有 DM 的成年人,在每个时间段内,最低 SEP 水平(教育程度和 IPR)的全因死亡率均明显高于最高 SEP 水平,表现出统计学显著的全因死亡率差距。然而,死亡率趋势和差距的模式因种族/族裔而异。归因于 DM 的超额死亡风险从 1997-2001 年显著下降到 2007-2011 年,在 SEP 水平内,以及在西班牙裔和非西班牙裔白人中;但在非西班牙裔黑人中没有统计学意义上的变化。

结论

美国成年人的全因死亡率有了实质性的改善。然而,尽管针对弱势群体进行了改善获得和护理质量的针对性努力,但我们观察到了不同种族/族裔群体或患有和不患有 DM 的成年人之间的 SEP 死亡率差距。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dc1/8098944/7a4b92c9df13/bmjopen-2020-044158f01.jpg

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