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血管加表面分类系统在根除后早期胃癌诊断中的应用价值。

Usefulness of vessel plus surface classification system for the diagnosis of early gastric cancer after eradication.

作者信息

Miyaoka Masaki, Yao Kenshi, Tanabe Hiroshi, Kanemitsu Takao, Imamura Kentaro, Ono Yoichiro, Ohtsu Kensei, Ishikawa Satoshi, Kojima Toshiki, Hasegawa Rino, Hirano Akikazu, Ikezono Go, Hisabe Takashi, Ueki Toshiharu, Ota Atsuko, Haraoka Seiji, Iwashita Akinori

机构信息

Department of Endoscopy (Masaki Miyaoka, Kenshi Yao, Takao Kanemitsu, Kentaro Imamura, Yoichiro Ono, Kensei Ohtsu, Satoshi Ishikawa, Toshiki Kojima, Rino Hasegawa, Akikazu Hirano, Go Ikezono).

Department of Pathology (Hiroshi Tanabe, Atsuko Ota, Seiji Haraoka, Akinori Iwashita), Fukuoka University Chikushi Hospital, Chikusino, Japan.

出版信息

Ann Gastroenterol. 2021;34(3):354-360. doi: 10.20524/aog.2021.0605. Epub 2021 Feb 26.

Abstract

BACKGROUND

It has been reported that it is sometimes difficult to make a diagnosis of gastric cancer detected after ) eradication. Therefore, we conducted a study to determine the usefulness of magnifying endoscopy using vessel plus surface classification system for making a diagnosis of early gastric cancer after eradication.

METHOD

Usefulness of the markers of the vessel plus surface classification system for diagnosing gastric cancer using magnifying endoscopy with narrow-band imaging was investigated for gastric cancer detected after eradication (-eradicated group) vs. -positive gastric cancer (-positive group).

RESULTS

85 lesions were included in this study. The -eradicated group comprised 27 lesions, whereas the -positive group comprised 58 lesions. As for magnified endoscopic findings based on the vessel plus surface classification system, the respective positivity rates in the -eradicated group vs. those in the -positive group were as follows: demarcation line, 100% (27/27) vs. 100% (58/58); irregular microvascular pattern, 100% (27/27) vs. 100% (58/58); and irregular microsurface pattern, 78% (21/27) vs. 95% (55/58). There was no significant difference in the positivity rates of the demarcation line and irregular microvascular pattern between the groups. The positivity rate of the irregular microsurface pattern was significantly lower in the -eradicated group than in the -positive group (P0.03).

CONCLUSION

We presume that the microvascular pattern is more useful than the microsurface pattern as a diagnostic marker in cases of gastric cancer detected after eradication.

摘要

背景

据报道,有时难以对根除治疗后检测出的胃癌进行诊断。因此,我们开展了一项研究,以确定使用血管加表面分类系统的放大内镜检查在诊断根除治疗后的早期胃癌中的作用。

方法

研究了血管加表面分类系统的标志物在使用窄带成像放大内镜检查诊断根除治疗后检测出的胃癌(根除治疗组)与幽门螺杆菌阳性胃癌(幽门螺杆菌阳性组)中的作用。

结果

本研究纳入85个病变。根除治疗组包括27个病变,而幽门螺杆菌阳性组包括58个病变。关于基于血管加表面分类系统的放大内镜检查结果,根除治疗组与幽门螺杆菌阳性组各自的阳性率如下:分界线,100%(27/27)对100%(58/58);不规则微血管形态,100%(27/27)对100%(58/58);以及不规则微表面形态,78%(21/27)对95%(55/58)。两组之间分界线和不规则微血管形态的阳性率无显著差异。根除治疗组不规则微表面形态的阳性率显著低于幽门螺杆菌阳性组(P<0.03)。

结论

我们推测,在根除治疗后检测出的胃癌病例中,微血管形态作为诊断标志物比微表面形态更有用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f986/8079864/d866fee20938/AnnGastroenterol-34-354-g001.jpg

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